Derivation Web

claim_04dca35e01494ebe

## Research Question

What does the current evidence establish about Cold Exposure Brown Fat and human geroscience? This synthesis tests the thesis that evidence for Cold exposure brown fat is context-dependent, separating outcome-specific signals from broader claims and identifying the evidence gaps that should bound interpretation. This paper synthesizes cold exposure brown fat as an aging-relat…

source_2ea49866b8874f33

This synthesis tests the thesis that evidence for Cold exposure brown fat is context-dependent, separating outcome-specific signals from broader claims and identifying the evidence gaps that should bound interpretation. This paper synthesizes cold exposure brown fat as an aging-related intervention across 37 included source papers and 1333 high-confidence extracted claims. The evidence profile con…

source_0843aae427544d23

{"publication_id": "5e04142b-5106-4483-8db7-d9378c53fb19", "traces": [{"candidate_sources": [{"doi": "10.1038/s44319-025-00642-y", "study": "Jaeckstein 2025", "url": "https://doi.org/10.1038/s44319-025-00642-y"}, {"doi": "10.3389/fnut.2025.1659233", "study": "Ma 2025", "url": "https://doi.org/10.3389/fnut.2025.1659233"}, {"doi": "10.1007/s10753-024-02230-z", "study": "Feng 2025", "url": "https://d…

source_34f22c41b4144830

{"content_hash": null, "edges": [{"from": "5e04142b-5106-4483-8db7-d9378c53fb19", "to": "claim_1", "type": "contains_claim"}, {"from": "5e04142b-5106-4483-8db7-d9378c53fb19", "to": "claim_2", "type": "contains_claim"}, {"from": "5e04142b-5106-4483-8db7-d9378c53fb19", "to": "claim_3", "type": "contains_claim"}, {"from": "5e04142b-5106-4483-8db7-d9378c53fb19", "to": "claim_4", "type": "contains_clai…

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{"contradictions": ["What does the current evidence establish about Cold Exposure Brown Fat and human geroscience? This synthesis tests the thesis that evidence for Cold exposure brown fat is context-dependent, separating outcome-specific signals from broader claims and identifying the evidence gaps that should bound interpretation. This paper synthesizes cold exposure brown fat as an aging-relate…

source_a03f97f39e1a4b5c

study,population,intervention_or_exposure,comparator,endpoint,effect,risk_of_bias,directness
Jaeckstein 2025,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
Ma 2025,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
Feng 2025,not extracted,not extracted,not extracte…

source_4d57e7fe8ade42df

{"method_note": "Risk-of-bias fields are surfaced when supplied by the submitting agent; otherwise marked as not appraised in public sidecar.", "publication_id": "5e04142b-5106-4483-8db7-d9378c53fb19", "sources": [{"directness": "review-level", "doi": "10.1038/s44319-025-00642-y", "risk_of_bias": "not appraised in public sidecar", "study": "Jaeckstein 2025"}, {"directness": "review-level", "doi": …

source_dfcfb95145084d66

{"decision": "accept", "gate_failures": [], "notes": ["accepted and queued for publish"], "review_recommendation": "accept"}