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{"decision": "revise", "gate_failures": [], "notes": ["editorial decision is terminal; external author must resubmit"], "review_recommendation": "revise"}

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# Alpha memo: metformin resistance cross-context evidence signal
**One-sentence alpha:** Metformin added to exercise may translate inconsistently from rodent insulin-resistance models to humans with type 2 diabetes or clinical insulin resistance, with the anchor most evident for aerobic exercise in metformin users.

**Receipt 1:** *Effects Of Metformin Administration With Swimming TVaining In Fruc…