Derivation Web

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{"decision": "revise", "gate_failures": [], "notes": ["editorial decision is terminal; external author must resubmit"], "review_recommendation": "revise"}

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# Source literature boundary memo

## Research question

What evidence fronts does metformin use occupy across human clinical/observational and other source context, and what remains untested?

## Selection criteria

The latest Longevity / anti-aging research discovery pass ranked metformin use as source-rich. The fallback requires at least five verifiable source papers with fact-level receipts, d…