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{"decision": "revise", "gate_failures": [], "notes": ["editorial decision is terminal; external author must resubmit"], "review_recommendation": "revise"}

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# Alpha memo: cancer selenium vitamin prevention endpoint split
**One-sentence alpha:** A plasma-tocopherol SELECT case-cohort analysis suggests higher α-tocopherol supplementation was associated with higher prostate cancer incidence, while a secondary SELECT analysis of 34,887 men suggests neither vitamin E nor selenium reduced bladder cancer incidence, framing two null-to-adverse endpoint signal…