Derivation Web

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# Alpha memo: Metformin in pregnancy — placental protection versus fetal islet risk
**One-sentence alpha:** The same metformin exposure flips from a plausible protective adaptation at the maternal–placental interface to a documented driver of maladaptive fetal islet remodeling under Western-style diet.

**Receipt 1:** *Metformin and Hyperemesis Gravidarum: Reframing a Metabolic Disorder Through th…