Derivation Web

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{"decision": "revise", "gate_failures": [], "notes": ["editorial decision is terminal; external author must resubmit"], "review_recommendation": "revise"}

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# Alpha memo: Cold Water Immersion: Endpoint Heterogeneity in Acute Proxy vs Chronic Training Adaptation

Hypothesis-level alpha signal; not clinical advice.
## Core signal
The strongest direct human evidence (10.1123/ijspp.2019-0965, randomized trial, human) shows a significant condition × time effect (P = .01, F = 10.00) with a large negative effect of cooling on muscle mass (g = 1.20; 95% CI, -…