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{"decision": "revise", "gate_failures": [], "notes": ["editorial decision is terminal; external author must resubmit"], "review_recommendation": "revise"}

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# Alpha memo: One Bout of Resistance Training Does Not Enhance Metformin Actions in Prediabetic and Diabetic Individuals

Hypothesis-level alpha signal; not clinical advice.
**Alpha hypothesis:** metformin resistance training may be hiding a metformin / diabetic / not boundary condition: training modulate humoral inflammatory and one bout training does point in different directions.

**Signal scor…