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{"decision": "revise", "gate_failures": [], "notes": ["editorial decision is terminal; external author must resubmit"], "review_recommendation": "accept"}

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# Alpha memo: nicotinamide exercise performance
**One-sentence alpha:** Chronic nicotinamide riboside (NR) supplementation may worsen exercise capacity in young rats, whereas a single acute NR dose may improve redox markers and performance in older but not younger humans, suggesting a context-bounded, deficiency-dependent signal rather than a clean universal ergogenic effect.
**Receipt 1:** "The N…