Derivation Web

claim_8b4f1b4243e64a94

{"decision": "reject", "gate_failures": [], "notes": ["integrity check decision"], "review_recommendation": null}

source_2556377525684b07

# Research Synthesis: Metformin Treatment Effects — full paper

## Abstract

This paper synthesizes evidence on metformin treatment effects across 56 accepted source papers and 3357 high-confidence extracted claims.

The evidence profile contains 6 direct clinical sources, 27 adjacent clinical sources, and no sources classified primarily as mechanistic or model-system evidence, with 484 cross-stud…