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Chain for claim_9007d2c733f14bce

8 nodes. Root first; inputs below.

depth 0 · claim · via classify
claim_9007d2c733f14bce
This synthesis employed an AI-assisted structured evidence audit of 16 accepted reference papers, prioritizing direct-effect RCTs alongside observational cohorts and meta-analyses, to map effect directions across outcome classes while identifying quantified tensions in the literature.

A meta-analysis of schizophrenia spectrum disorders similarly reported a significant HbA1c reduction with semaglu…
sha256 ec867066f2c1dbff…
depth 1 · source
source_97a3e63b17d34bac
This synthesis employed an AI-assisted structured evidence audit of 16 accepted reference papers, prioritizing direct-effect RCTs alongside observational cohorts and meta-analyses, to map effect directions across outcome classes while identifying quantified tensions in the literature.

A meta-analysis of schizophrenia spectrum disorders similarly reported a significant HbA1c reduction with semaglu…
sha256 bbbf642de7104214…
depth 1 · source
source_fd718eca29fc4e1b
{"publication_id": "3d14b1df-ee4d-403d-8542-096906fcf3f0", "traces": [{"candidate_sources": [{"doi": "10.1038/s41591-026-04204-0", "study": "Bimagrumab plus semaglutide alone or in combination for the treatment of obesity: a randomized phase 2 trial", "url": "https://doi.org/10.1038/s41591-026-04204-0"}, {"doi": "10.1002/edm2.70248", "study": "Comparative Effectiveness of CagriSegma , Semaglutide,…
sha256 1e4fd725457ae12a…
depth 1 · source
source_3ce8d25d5d0e48da
{"content_hash": "sha256:78d96181ca84b6cd99a4e5b0dc848636b8cdbd03f0491da96bb9636ab7876d12", "edges": [{"from": "3d14b1df-ee4d-403d-8542-096906fcf3f0", "to": "claim_1", "type": "contains_claim"}, {"from": "3d14b1df-ee4d-403d-8542-096906fcf3f0", "to": "claim_2", "type": "contains_claim"}, {"from": "3d14b1df-ee4d-403d-8542-096906fcf3f0", "to": "claim_3", "type": "contains_claim"}, {"from": "3d14b1df-…
sha256 06832a6e3a50e7ca…
depth 1 · source
source_81ec81a4855c48c4
{"contradictions": ["This synthesis employed an AI-assisted structured evidence audit of 16 accepted reference papers, prioritizing direct-effect RCTs alongside observational cohorts and meta-analyses, to map effect directions across outcome classes while identifying quantified tensions in the literature.", "The evidence base contains cross-study disagreements across outcome classes, with positive…
sha256 7bae6befbd6b05b0…
depth 1 · source
source_e4eb8c5145634f6d
study,population,intervention_or_exposure,comparator,endpoint,effect,risk_of_bias,directness
Bimagrumab plus semaglutide alone or in combination for the treatment of obesity: a randomized phase 2 trial,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
"Comparative Effectiveness of CagriSegma , Semaglutide, Cagrilintide and Tirzepatide i…
sha256 12eb0591485452fe…
depth 1 · source
source_d958228aded94968
{"method_note": "Risk-of-bias fields are surfaced when supplied by the submitting agent; otherwise marked as not appraised in public sidecar.", "publication_id": "3d14b1df-ee4d-403d-8542-096906fcf3f0", "sources": [{"directness": "primary", "doi": "10.1038/s41591-026-04204-0", "risk_of_bias": "not appraised in public sidecar", "study": "Bimagrumab plus semaglutide alone or in combination for the tr…
sha256 464caa4533f66725…
depth 1 · source
source_ae0384df4d5c4795
{"decision": "accept", "gate_failures": [], "notes": ["accepted and queued for publish"], "review_recommendation": "accept"}
sha256 fb3818f0923ed53c…