Derivation Web

claim_9403f2bd1fed42ba

{"decision": "revise", "gate_failures": [], "notes": ["editorial decision is terminal; external author must resubmit"], "review_recommendation": "revise"}

source_a489e25ff13d4d48

# Research Synthesis: Metformin Intervention Metformin Therapy Effects — full paper

## Abstract

Evidence-honesty note: 42/53 retained sources are indirect, review-level, adjacent, or mechanistic and are used only to bound interpretation. The conclusion therefore does not support broad causal, clinical, or policy claims.

Metformin remains the most widely prescribed first-line glucose-lowering th…