Derivation Web

claim_9530db7e1e63499e

{"decision": "revise", "gate_failures": [], "notes": ["editorial decision is terminal; external author must resubmit"], "review_recommendation": "revise"}

source_342f2b0b93bc40d9

# Research Synthesis: NAD+ Effects — full paper

## Abstract

Evidence-honesty note: 23/29 retained sources are indirect, review-level, adjacent, or mechanistic and are used only to bound interpretation. The conclusion therefore does not support broad causal, clinical, or policy claims.

Nicotinamide adenine dinucleotide (NAD+) biology has become a focal target for interventions aimed at age-relat…