Derivation Web

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{"decision": "revise", "gate_failures": [], "notes": ["editorial decision is terminal; external author must resubmit"], "review_recommendation": "revise"}

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# Source literature boundary memo

## Research question

Across retrieved fact-level receipts for metformin use, which endpoints show directionally favorable versus null/non-convergent signals, and what matched PICO remains untested?

## Selection criteria

The source-literature fallback selected metformin use because the domain snapshot exposed enough fact-backed, topic-overlapping papers. The fa…