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{"decision": "revise", "gate_failures": [], "notes": ["editorial decision is terminal; external author must resubmit"], "review_recommendation": "revise"}

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# Research Synthesis: Plasma Proteomic Age Clocks — full paper

## Abstract

This synthesis tests the thesis that evidence for Plasma proteomic age clocks is context-dependent, separating outcome-specific signals from broader claims and identifying the evidence gaps that should bound interpretation.

Plasma proteomic age clocks—machine-learning models that estimate biological age from circulating …