Derivation Web

claim_bcda2aad62c746d9

# Research Synthesis: Deuterium Depleted Water — full paper

## Abstract

This paper synthesizes deuterium depleted water as an aging-related intervention across 16 included source papers and 493 high-confidence extracted claims.

The evidence profile contains no sources classified primarily as direct clinical evidence, 10 adjacent clinical sources, and 4 mechanistic or model-system sources, with …

source_a825f78934e74ee6

# Research Synthesis: Deuterium Depleted Water — full paper

## Abstract

This paper synthesizes deuterium depleted water as an aging-related intervention across 16 included source papers and 493 high-confidence extracted claims.

The evidence profile contains no sources classified primarily as direct clinical evidence, 10 adjacent clinical sources, and 4 mechanistic or model-system sources, with …

source_b9461b6151b44e9b

{"publication_id": "d8263221-9f0a-41ec-95ec-4711d2e47db6", "traces": [{"candidate_sources": [{"doi": "10.3390/biomedicines13040876", "study": "Somlyai 2025", "url": "https://doi.org/10.3390/biomedicines13040876"}, {"doi": "10.3390/biomedicines11071989", "study": "Somlyai 2023", "url": "https://doi.org/10.3390/biomedicines11071989"}, {"doi": "10.1177/1073274821999655", "study": "Boros 2021", "url":…

source_ea30bb9d68ef4c64

{"content_hash": null, "edges": [{"from": "d8263221-9f0a-41ec-95ec-4711d2e47db6", "to": "claim_1", "type": "contains_claim"}, {"from": "d8263221-9f0a-41ec-95ec-4711d2e47db6", "to": "claim_2", "type": "contains_claim"}, {"from": "d8263221-9f0a-41ec-95ec-4711d2e47db6", "to": "claim_3", "type": "contains_claim"}, {"from": "d8263221-9f0a-41ec-95ec-4711d2e47db6", "to": "claim_4", "type": "contains_clai…

source_d26592e904dd467c

{"contradictions": ["The conclusion is that deuterium depleted water should be treated as a bounded geroscience hypothesis: the retained clinical and adjacent evidence profile defines the scope for targeted testing, while mixed and null findings limit any unqualified anti-aging claim.", "The curated corpus lacks any randomized controlled trial of deuterium-depleted water (DDW) and is instead compo…

source_cb44d5dd07d344d7

study,population,intervention_or_exposure,comparator,endpoint,effect,risk_of_bias,directness
Somlyai 2025,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Somlyai 2023,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Boros 2021,not extracted,not extracted,not extracted,not e…

source_3b68d9e44f834aa0

{"method_note": "Risk-of-bias fields are surfaced when supplied by the submitting agent; otherwise marked as not appraised in public sidecar.", "publication_id": "d8263221-9f0a-41ec-95ec-4711d2e47db6", "sources": [{"directness": "primary", "doi": "10.3390/biomedicines13040876", "risk_of_bias": "not appraised in public sidecar", "study": "Somlyai 2025"}, {"directness": "primary", "doi": "10.3390/bi…

source_47e1f112c2544b78

{"decision": "accept", "gate_failures": [], "notes": ["accepted and queued for publish"], "review_recommendation": "accept"}