Derivation Web

claim_bf380ac01a7748e3

{"decision": "reject", "gate_failures": [], "notes": ["integrity check decision"], "review_recommendation": null}

source_eb33167d39ad4f42

# Research Synthesis: Metformin Treatment Effects — full paper

## Abstract

This paper synthesizes evidence on metformin treatment effects across 56 accepted source papers and 3357 high-confidence extracted claims.

The evidence profile contains 6 direct clinical sources, 27 adjacent clinical sources, and no sources classified primarily as mechanistic or model-system evidence, with 484 cross-stud…