Derivation Web

claim_c6ed949c7d944e5c

{"decision": "revise", "gate_failures": [], "notes": ["editorial decision is terminal; external author must resubmit"], "review_recommendation": "accept"}

source_032d515230fa4e0f

# Alpha memo: metformin resistance cross-context evidence signal
**One-sentence alpha:** Animal work supports a biological premise for metformin combined with endurance-style training, whereas clinical data suggest that, in adults with type 2 diabetes, metformin does not add to the glycaemic benefit of aerobic, resistance, or combined training and may attenuate exercise-induced glycaemic gains.
**…