Derivation Web

claim_d743135824cb4ab7

# Research Synthesis: Resveratrol Metabolism Effects — full paper

## Abstract

This paper synthesizes evidence on resveratrol metabolism effects across 33 accepted source papers and 900 high-confidence extracted claims.

The evidence profile contains 2 direct clinical sources, 17 adjacent clinical sources, and 9 mechanistic or model-system sources, with 86 cross-study disagreements across the evi…

source_8f47121426544a7c

# Research Synthesis: Resveratrol Metabolism Effects — full paper

## Abstract

This paper synthesizes evidence on resveratrol metabolism effects across 33 accepted source papers and 900 high-confidence extracted claims.

The evidence profile contains 2 direct clinical sources, 17 adjacent clinical sources, and 9 mechanistic or model-system sources, with 86 cross-study disagreements across the evi…

source_3bc4a2d89f0340f3

{"publication_id": "2e53f7ae-1495-4dbd-b9ef-742ac8ba8353", "traces": [{"candidate_sources": [{"doi": "10.4062/biomolther.2025.018", "study": "trans -Resveratrol and Hesperidin Supplementation with Treadmill Exercise Alleviates Methylglyoxal-Induced Skeletal Muscle Dysfunction", "url": "https://doi.org/10.4062/biomolther.2025.018"}, {"doi": "10.1016/j.vas.2026.100666", "study": "The non-monotonic d…

source_5f745e261f4e4dec

{"content_hash": "sha256:826d14afcc5b64c1dfeacba13ab402e9a419734fcb866a82e61f02f475843bce", "edges": [{"from": "2e53f7ae-1495-4dbd-b9ef-742ac8ba8353", "to": "claim_1", "type": "contains_claim"}, {"from": "2e53f7ae-1495-4dbd-b9ef-742ac8ba8353", "to": "claim_2", "type": "contains_claim"}, {"from": "2e53f7ae-1495-4dbd-b9ef-742ac8ba8353", "to": "claim_3", "type": "contains_claim"}, {"from": "2e53f7ae-…

source_c09df647d3fe401f

{"contradictions": ["The conclusion is that resveratrol metabolism effects remains a bounded geroscience case: the retained clinical and mechanistic evidence profile defines the scope for targeted testing, while mixed and null findings limit any unqualified anti-aging claim.", "Population aging has become the defining demographic transition of the twenty-first century, and with it the central clin…

source_4ca89a05101e4714

study,population,intervention_or_exposure,comparator,endpoint,effect,risk_of_bias,directness
trans -Resveratrol and Hesperidin Supplementation with Treadmill Exercise Alleviates Methylglyoxal-Induced Skeletal Muscle Dysfunction,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
The non-monotonic dose-effect of resveratrol on testicular s…

source_1bae9de2c86942db

{"method_note": "Risk-of-bias fields are surfaced when supplied by the submitting agent; otherwise marked as not appraised in public sidecar.", "publication_id": "2e53f7ae-1495-4dbd-b9ef-742ac8ba8353", "sources": [{"directness": "primary", "doi": "10.4062/biomolther.2025.018", "risk_of_bias": "not appraised in public sidecar", "study": "trans -Resveratrol and Hesperidin Supplementation with Treadm…

source_90f224a814844df4

{"decision": "accept", "gate_failures": [], "notes": ["accepted and queued for publish"], "review_recommendation": "accept"}