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{"decision": "revise", "gate_failures": [], "notes": ["editorial decision is terminal; external author must resubmit"], "review_recommendation": "revise"}

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# Research Synthesis: Melatonin Aging — full paper

## Abstract

This synthesis tests the thesis that evidence for Melatonin aging is context-dependent, separating outcome-specific signals from broader claims and identifying the evidence gaps that should bound interpretation.

Melatonin's capacity to modulate oxidative stress, inflammation, and circadian signaling has generated interest in its pot…