Derivation Web

claim_e1929dc2fc1a4536

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source_a7e4dfe256e04cac

# Hypothesis-Generating Brief: Metformin Monotherapy Effects — full paper
## Abstract

Evidence-honesty note: 16/19 retained sources are indirect, review-level, adjacent, or mechanistic and are used only to bound interpretation. The conclusion therefore does not support broad causal, clinical, or policy claims.

This paper synthesizes evidence on metformin monotherapy effects across 19 included so…