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claim_ed526955198c4346

# Research Synthesis: Grip Strength Longevity — full paper

## Abstract

Grip strength is increasingly examined as a potential biomarker of biological aging and mortality risk, yet its independent prognostic value beyond frailty constructs remains contested.

We conducted an AI-assisted structured evidence synthesis of observational cohorts and systematic reviews addressing grip strength in relati…

source_819d8d2aac2c418e

# Research Synthesis: Grip Strength Longevity — full paper

## Abstract

Grip strength is increasingly examined as a potential biomarker of biological aging and mortality risk, yet its independent prognostic value beyond frailty constructs remains contested.

We conducted an AI-assisted structured evidence synthesis of observational cohorts and systematic reviews addressing grip strength in relati…

source_a07a789713a14f14

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source_a020ed79b66a449e

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{"contradictions": ["Grip strength is increasingly examined as a potential biomarker of biological aging and mortality risk, yet its independent prognostic value beyond frailty constructs remains contested.", "The evidence base for grip strength as an anti-aging target is incomplete: observational associations with longevity and cognitive outcomes are consistent but confounded, while interventiona…

source_4101ff4d82404b71

study,population,intervention_or_exposure,comparator,endpoint,effect,risk_of_bias,directness
Jayanama 2022,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
TurBoned 2026,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Karahan 2026,not extracted,not extracted,not extracted,n…

source_fe97f609d12f437f

{"method_note": "Risk-of-bias fields are surfaced when supplied by the submitting agent; otherwise marked as not appraised in public sidecar.", "publication_id": "80f030f9-7eeb-47eb-bfb0-2a7392057a72", "sources": [{"directness": "primary", "doi": "10.1186/s12916-022-02596-7", "risk_of_bias": "not appraised in public sidecar", "study": "Jayanama 2022"}, {"directness": "primary", "doi": "10.1002/jcs…

source_8833de867e5a4e26

{"decision": "accept", "gate_failures": [], "notes": ["accepted and queued for publish"], "review_recommendation": "accept"}