Derivation Web

source_113fd2f11f9747ac

by researka:v2 · 2026-06-17 00:07:01.836225+04:00

study,population,intervention_or_exposure,comparator,endpoint,effect,risk_of_bias,directness
Metabolic and Orexin-A Responses to Ketogenic Diet and Intermittent Fasting: A 12-Month Randomized Trial in Adults with Obesity,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
Age-Specific Analysis of the Effects of Intermittent Fasting on Body Composition and Cardiometabolic Markers in Healthy Adults and Individuals with Overweight or Obesity: A Systematic Review and Meta-Analysis of Randomized Controlled Trials,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
Intermittent fasting improves metabolic outcomes in metabolic syndrome: a systematic review and meta-analysis with GRADE evaluation,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
Time‐Restricted Feeding Preserves Synaptic Function and Modulates Reelin and α ‐Synuclein in an Acute Amyloid‐ β Rat Model: A Comparative Study With Alternate‐Day Fasting,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Optimal dosage of exercise combined with intermittent fasting for body composition and cardiometabolic health in adults: a systematic review and multilevel meta-analysis,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
The effectiveness of fasting regimens on serum levels of some major weight regulating hormones: a GRADE-assessed systematic review and meta-analysis in randomized controlled trial,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
Effects of Time-Restricted Fasting–Nicotinamide Mononucleotide Combination on Exercise Capacity via Mitochondrial Activation and Gut Microbiota Modulation,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Intermittent Fasting Enhances Genome Integrity and Cytoprotective Pathways via (BHB) β‐Hydroxybutyrate Signaling and Chromatin Remodeling,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
"Uncovering shared and tissue-specific molecular adaptations to intermittent fasting in liver, brain, and muscle",not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Genetic regulation of fasting-induced longevity effects,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Simulation Effect and Mechanism of High-Polymeric Persimmon Tannin on Simulating Alternate-Day Fasting on Regulating Lipid Metabolism in Obese Mice,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Alternate Day Fasting Enhances Intestinal Epithelial Function During Aging by Regulating Mitochondrial Metabolism,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Adipose Inositol Monophosphate Metabolism Is Associated with Fasting Regimen-Elicited Metabolic Benefits,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Therapeutic Potential of Various Intermittent Fasting Regimens in Alleviating Type 2 Diabetes Mellitus and Prediabetes: A Narrative Review,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
"**Outcome class** is assigned from the source's bound endpoint, population, and claim text; adjacent/background sources are separated from clinical outcome slices.",not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
"**Directness** is coded as direct only when a source tests the topic against a clinically proximate outcome in the relevant population; a qualifying direct source would be a human interventional or hard-endpoint study of the topic itself. Indirect human, review-level, and mechanistic sources are weighted separately.",not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
"**Directional signal** is counted within the assigned outcome class only. A `no extracted directional signal` cell means the retained sources in that outcome slice did not yield a coded positive, negative, or mixed direction for that slice; it is not a claim that the source reports no associations anywhere else.",not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
**Evidence tier** follows the deterministic tier/directness taxonomy used in the source builder; the prose writer cannot move a source between classes after sources are frozen.,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
Studenski 2011,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
Cesari 2009,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
Perera 2006,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
ADA 2024,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
WHO 2000,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
Bohannon 1997,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
Cruz-Jentoft 2019,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
Tinetti 1988,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
Tancredi 2015,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
Ioannidis 2005,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation

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