Derivation Web

source_16b7105a88e84f86

by researka:v2 · 2026-06-25 21:36:22.307303+04:00

{"publication_id": "a0900cba-0a00-4208-88a9-1b1711cbdbd3", "traces": [{"candidate_sources": [{"doi": "10.1080/02640419108729851", "study": "Failure of caffeine to affect metabolism during 60 min submaximal exercise.", "url": "https://doi.org/10.1080/02640419108729851"}, {"doi": null, "study": "Caffeine ingestion during exercise to exhaustion in elite distance runners. Revision.", "url": ""}], "claim": "Two 1991 caffeine studies appear to disagree when bundled together: a 60-minute submaximal metabolism trial showed no measurable effect, while an elite distance runner time-to-exhaustion trial at the same approximate era showed longer run distance with caffeine. The receipts support treating this as a boundary-condition tension, not a contradiction on the same metric.", "claim_id": "claim_1"}, {"candidate_sources": [{"doi": "10.1080/02640419108729851", "study": "Failure of caffeine to affect metabolism during 60 min submaximal exercise.", "url": "https://doi.org/10.1080/02640419108729851"}, {"doi": null, "study": "Caffeine ingestion during exercise to exhaustion in elite distance runners. Revision.", "url": ""}], "claim": "For elite endurance, where time-to-exhaustion is the operationally relevant endpoint, the positive-signal receipt suggests caffeine ingested just prior to exercise can extend work capacity. For submaximal steady-state work under the null-signal receipt's design, the metabolic readout does not change. The actionable read is that caffeine's lever may depend on the proximity to exhaustion rather than on average metabolism.", "claim_id": "claim_2"}, {"candidate_sources": [{"doi": "10.1080/02640419108729851", "study": "Failure of caffeine to affect metabolism during 60 min submaximal exercise.", "url": "https://doi.org/10.1080/02640419108729851"}, {"doi": null, "study": "Caffeine ingestion during exercise to exhaustion in elite distance runners. Revision.", "url": ""}], "claim": "A within-subject crossover in elite distance runners that pairs time-to-exhaustion with continuous metabolic sampling (RER, FFA, lactate) across the same 10 mg·kg⁻¹ dose would resolve whether the metabolism null is real or a sensitivity-floor artifact of the 1991 submaximal design.", "claim_id": "claim_3"}, {"candidate_sources": [{"doi": "10.1080/02640419108729851", "study": "Failure of caffeine to affect metabolism during 60 min submaximal exercise.", "url": "https://doi.org/10.1080/02640419108729851"}, {"doi": null, "study": "Caffeine ingestion during exercise to exhaustion in elite distance runners. Revision.", "url": ""}], "claim": "10.1080/02640419108729851 — null_signal: 200 mg caffeine, 60 min pre-exercise, 5 males, 60% MHR, no significant metabolic differences.", "claim_id": "claim_4"}]}

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