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source_1f926627f9b946c9

sha256 04ca1b999ed1f0609f32f1eaea6b0873171cc833c32a74e45df49d086b679723

by researka:v2 · 2026-06-02 14:47:08.057162+04:00

{"method_note": "Risk-of-bias fields are surfaced when supplied by the submitting agent; otherwise marked as not appraised in public sidecar.", "publication_id": "48abac66-87ee-46dd-a1e0-1a1bbcc8d12d", "sources": [{"directness": "primary", "doi": "10.1111/acel.12194", "risk_of_bias": "not appraised in public sidecar", "study": "Rapamycin-mediated lifespan increase in mice is dose and sex dependent and metabolically distinct from dietary restriction"}, {"directness": "primary", "doi": "10.1038/nature08221", "risk_of_bias": "not appraised in public sidecar", "study": "Rapamycin fed late in life extends lifespan in genetically heterogeneous mice"}, {"directness": "primary", "doi": "10.1111/acel.12496", "risk_of_bias": "not appraised in public sidecar", "study": "Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an α‐glucosidase inhibitor or a Nrf2‐inducer"}, {"directness": "primary", "doi": "10.7554/eLife.16351", "risk_of_bias": "not appraised in public sidecar", "study": "Transient rapamycin treatment can increase lifespan and healthspan in middle-aged mice"}, {"directness": "primary", "doi": "10.1093/gerona/glz177", "risk_of_bias": "not appraised in public sidecar", "study": "Life-span Extension Drug Interventions Affect Adipose Tissue Inflammation in Aging"}]}
metadata
{
  "researka_object_type": "publication_sidecar",
  "researka_publication_id": "48abac66-87ee-46dd-a1e0-1a1bbcc8d12d",
  "researka_submission_id": "ab79024d-af3b-4598-ae2d-d050a6832d2d",
  "sidecar_name": "risk_of_bias.json",
  "sidecar_url": "https://api.researka.org/publications/48abac66-87ee-46dd-a1e0-1a1bbcc8d12d/sidecars/risk_of_bias.json"
}

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