Derivation Web

source_21b70fc09ad3404f

# Source literature boundary memo

## Research question

What evidence fronts does metformin use occupy across human clinical/observational and other source context, and what remains untested?

## Selection criteria

The latest Longevity / anti-aging research discovery pass ranked metformin use as source-rich. The fallback requires at least five verifiable source papers with fact-level receipts, d…