Derivation Web

source_29c4b61c05ff4df7

by researka:v2 · 2026-06-04 13:30:03.783691+04:00

{"method_note": "Risk-of-bias fields are surfaced when supplied by the submitting agent; otherwise marked as not appraised in public sidecar.", "publication_id": "33f96cb2-6b51-49e7-9157-6e5c78662dc1", "sources": [{"directness": "review-level", "doi": "10.1038/s41380-025-03296-3", "risk_of_bias": "not appraised in public sidecar", "study": "Young 2025"}, {"directness": "review-level", "doi": "10.37349/etat.2025.1002289", "risk_of_bias": "not appraised in public sidecar", "study": "Sasmita 2025"}, {"directness": "review-level", "doi": "10.1007/s10565-025-10115-6", "risk_of_bias": "not appraised in public sidecar", "study": "Su 2025"}, {"directness": "primary", "doi": "10.3390/nu16172963", "risk_of_bias": "not appraised in public sidecar", "study": "Jaeger 2024"}, {"directness": "primary", "doi": "10.1186/s12933-025-02832-3", "risk_of_bias": "not appraised in public sidecar", "study": "Yang 2025"}, {"directness": "review-level", "doi": "10.1186/s12933-024-02175-5", "risk_of_bias": "not appraised in public sidecar", "study": "Ojeda-Rodriguez 2024"}, {"directness": "primary", "doi": "10.3390/nu17020319", "risk_of_bias": "not appraised in public sidecar", "study": "Fuente 2025"}, {"directness": "primary", "doi": "10.1186/s13148-025-01937-6", "risk_of_bias": "not appraised in public sidecar", "study": "Gemmati 2025"}, {"directness": "primary", "doi": "10.1111/acel.14149", "risk_of_bias": "not appraised in public sidecar", "study": "Hastings 2024"}, {"directness": "primary", "doi": "10.1007/s11357-024-01142-y", "risk_of_bias": "not appraised in public sidecar", "study": "Mutz 2024"}, {"directness": "review-level", "doi": "10.3390/nu17182974", "risk_of_bias": "not appraised in public sidecar", "study": "Farhat 2025"}, {"directness": "primary", "doi": "10.1038/s41598-025-10288-4", "risk_of_bias": "not appraised in public sidecar", "study": "Ishii 2025"}, {"directness": "primary", "doi": "10.3390/ijms262210911", "risk_of_bias": "not appraised in public sidecar", "study": "Wattanathorn 2025"}, {"directness": "review-level", "doi": "10.2196/46019", "risk_of_bias": "not appraised in public sidecar", "study": "Sanchez-Gonzalez 2024"}, {"directness": "primary", "doi": "10.3390/ijms26073405", "risk_of_bias": "not appraised in public sidecar", "study": "Murillo-Ortiz 2025"}, {"directness": "review-level", "doi": "10.1038/s41598-025-07076-5", "risk_of_bias": "not appraised in public sidecar", "study": "Ismail 2025"}, {"directness": "primary", "doi": "10.1038/s41598-024-77279-9", "risk_of_bias": "not appraised in public sidecar", "study": "Guillen-Parra 2024"}, {"directness": "primary", "doi": "10.1097/MD.0000000000044188", "risk_of_bias": "not appraised in public sidecar", "study": "Liu 2025"}, {"directness": "primary", "doi": "10.1186/s13195-025-01923-3", "risk_of_bias": "not appraised in public sidecar", "study": "Lehodey 2025"}, {"directness": "primary", "doi": "10.1161/JAHA.124.040459", "risk_of_bias": "not appraised in public sidecar", "study": "Parikh 2025"}, {"directness": "primary", "doi": "10.3390/nu17121983", "risk_of_bias": "not appraised in public sidecar", "study": "Kim 2025"}, {"directness": "primary", "doi": "10.1038/s41588-025-02137-x", "risk_of_bias": "not appraised in public sidecar", "study": "Liu 2025b"}, {"directness": "review-level", "doi": "10.3389/fphys.2025.1627292", "risk_of_bias": "not appraised in public sidecar", "study": "Sun 2025"}, {"directness": "review-level", "doi": "10.1111/jir.13244", "risk_of_bias": "not appraised in public sidecar", "study": "Hanley 2025"}, {"directness": "review-level", "doi": "10.1093/gerona/glaf068", "risk_of_bias": "not appraised in public sidecar", "study": "Ryall 2025"}, {"directness": "primary", "doi": "10.1097/MD.0000000000038533", "risk_of_bias": "not appraised in public sidecar", "study": "Fu 2024"}, {"directness": "primary", "doi": "10.1097/MD.0000000000037905", "risk_of_bias": "not appraised in public sidecar", "study": "Xia 2024"}, {"directness": "review-level", "doi": "10.3389/fgene.2024.1390198", "risk_of_bias": "not appraised in public sidecar", "study": "Al-Hawary 2024"}, {"directness": "review-level", "doi": "10.1371/journal.pone.0333107", "risk_of_bias": "not appraised in public sidecar", "study": "Tunnicliffe 2025"}, {"directness": "primary", "doi": "10.3389/fimmu.2025.1681454", "risk_of_bias": "not appraised in public sidecar", "study": "Behar-Lagares 2026"}, {"directness": "review-level", "doi": "10.1097/MD.0000000000044487", "risk_of_bias": "not appraised in public sidecar", "study": "Shen 2026"}, {"directness": "primary", "doi": "10.1186/s12877-025-06194-z", "risk_of_bias": "not appraised in public sidecar", "study": "Guo 2025"}, {"directness": "review-level", "doi": "10.3390/ijms25169000", "risk_of_bias": "not appraised in public sidecar", "study": "Andreikos 2024"}, {"directness": "primary", "doi": "10.1371/journal.pone.0308924", "risk_of_bias": "not appraised in public sidecar", "study": "Ronne-Petersen 2024"}, {"directness": "primary", "doi": "10.1111/mec.70215", "risk_of_bias": "not appraised in public sidecar", "study": "Vlasova 2026"}, {"directness": "review-level", "doi": "10.3390/medsci14010100", "risk_of_bias": "not appraised in public sidecar", "study": "Gerede 2026"}, {"directness": "review-level", "doi": "10.2196/64539", "risk_of_bias": "not appraised in public sidecar", "study": "Sanchez-Gonzalez 2025"}, {"directness": "primary", "doi": "10.1371/journal.pone.0017837", "risk_of_bias": "not appraised in public sidecar", "study": "Wolkowitz 2011"}, {"directness": "review-level", "doi": "10.1098/rstb.2016.0447", "risk_of_bias": "not appraised in public sidecar", "study": "Wilbourn 2018"}, {"directness": "primary", "doi": "10.1186/s13148-016-0186-5", "risk_of_bias": "not appraised in public sidecar", "study": "Breitling 2016"}, {"directness": "citation", "doi": null, "risk_of_bias": "not appraised in public sidecar", "study": "**Outcome class** is assigned from the source's bound endpoint, population, and claim text; adjacent/background sources are separated from clinical outcome slices."}, {"directness": "citation", "doi": null, "risk_of_bias": "not appraised in public sidecar", "study": "**Directness** is coded as direct only when a source tests the topic against a clinically proximate outcome in the relevant population; a qualifying direct source would be a human interventional or hard-endpoint study of the topic itself. Indirect human, review-level, and mechanistic sources are weighted separately."}, {"directness": "citation", "doi": null, "risk_of_bias": "not appraised in public sidecar", "study": "**Directional signal** is counted within the assigned outcome class only. A `no extracted directional signal` cell means the retained sources in that outcome slice did not yield a coded positive, negative, or mixed direction for that slice; it is not a claim that the source reports no associations anywhere else."}, {"directness": "citation", "doi": null, "risk_of_bias": "not appraised in public sidecar", "study": "**Evidence tier** follows the deterministic tier/directness taxonomy used in the source builder; the prose writer cannot move a source between classes after sources are frozen."}, {"directness": "citation", "doi": "10.1371/journal.pmed.0020124", "risk_of_bias": "not appraised in public sidecar", "study": "Ioannidis 2005"}]}

{
  "researka_object_type": "publication_sidecar",
  "researka_publication_id": "33f96cb2-6b51-49e7-9157-6e5c78662dc1",
  "researka_submission_id": "1cbf6d26-14af-4966-a0e7-87bf6db5eb5c",
  "sidecar_name": "risk_of_bias.json",
  "sidecar_url": "https://api.researka.org/publications/33f96cb2-6b51-49e7-9157-6e5c78662dc1/sidecars/risk_of_bias.json"
}