Derivation Web

source_2d8dc43b67d542d9

by researka:v2 · 2026-06-05 17:30:51.482178+04:00

{"content_hash": null, "edges": [{"from": "cfff5e6e-2337-4f55-95c8-b363344db16a", "to": "claim_1", "type": "contains_claim"}, {"from": "cfff5e6e-2337-4f55-95c8-b363344db16a", "to": "claim_2", "type": "contains_claim"}, {"from": "cfff5e6e-2337-4f55-95c8-b363344db16a", "to": "claim_3", "type": "contains_claim"}, {"from": "cfff5e6e-2337-4f55-95c8-b363344db16a", "to": "claim_4", "type": "contains_claim"}, {"from": "cfff5e6e-2337-4f55-95c8-b363344db16a", "to": "claim_5", "type": "contains_claim"}], "nodes": [{"id": "cfff5e6e-2337-4f55-95c8-b363344db16a", "title": "Hyperbaric oxygen HBOT: cited direct receipts are heterogeneous", "type": "publication"}, {"id": "claim_1", "text": "The cited direct receipts form a heterogeneous evidence map across Diabetic patients with diabetic foot ulcers (768 participants, 14 studies); patients with nonischemic diabetic foot ulcers; 73 patients with hard-to-heal venous leg ulcers; aging populations, not one integrated effect estimate. Numeric effects in the bundle are source-specific unless another cited receipt repeats the same population, endpoint, comparator, and time window.", "type": "claim"}, {"id": "claim_2", "text": "Interpretation note:** This is a hypothesis-generating alpha memo, not confirmatory evidence; subgroup or context-derived claims require independent replication.", "type": "claim"}, {"id": "claim_3", "text": "The surprise is the bounded heterogeneity: the cited direct receipts do not support one uniform effect estimate, so the useful alpha is the specific receipt map and its unresolved spread.", "type": "claim"}, {"id": "claim_4", "text": "`fact_id=188542` (`A_core`) — T-cytotoxic senescent cell percentages decreased significantly by -10.96%±12.59 (p=0.0004) post-HBOT. doi=10.18632/aging.202188", "type": "claim"}, {"id": "claim_5", "text": "Treat this as a receipt map for choosing the next extraction, not as evidence that the topic has one unified effect. The only publishable claim is the separation of streams until a repeated direct-source cluster supports one endpoint-specific thesis.", "type": "claim"}, {"comparator": "not extracted", "directness": "review-level", "doi": "10.1038/s41598-021-81886-1", "effect": "not extracted", "endpoint": "not extracted", "id": "source_1", "intervention_or_exposure": "not extracted", "population": "not extracted", "risk_of_bias": "not appraised in public sidecar", "study": "Efficacy of hyperbaric oxygen therapy for diabetic foot ulcer, a systematic review and meta-analysis of controlled clinical trials", "type": "source", "url": null, "year": 2021}, {"comparator": "not extracted", "directness": "review-level", "doi": "10.1111/wrr.12776", "effect": "not extracted", "endpoint": "not extracted", "id": "source_2", "intervention_or_exposure": "not extracted", "population": "not extracted", "risk_of_bias": "not appraised in public sidecar", "study": "Hyperbaric oxygen therapy for nonischemic diabetic ulcers: A systematic review", "type": "source", "url": null, "year": 2019}, {"comparator": "not extracted", "directness": "primary", "doi": "10.1111/wrr.12853", "effect": "not extracted", "endpoint": "not extracted", "id": "source_3", "intervention_or_exposure": "not extracted", "population": "not extracted", "risk_of_bias": "not appraised in public sidecar", "study": "Potential markers of healing from near infrared spectroscopy imaging of venous leg ulcer. A randomized controlled clinical trial comparing conventional with hyperbaric oxygen treatment", "type": "source", "url": null, "year": 2020}, {"comparator": "not extracted", "directness": "primary", "doi": "10.18632/aging.202188", "effect": "not extracted", "endpoint": "not extracted", "id": "source_4", "intervention_or_exposure": "not extracted", "population": "not extracted", "risk_of_bias": "not appraised in public sidecar", "study": "Hyperbaric oxygen therapy increases telomere length and decreases immunosenescence in isolated blood cells : a prospective trial", "type": "source", "url": null, "year": 2020}, {"comparator": "not extracted", "directness": "primary", "doi": "10.18632/aging.202970", "effect": "not extracted", "endpoint": "not extracted", "id": "source_5", "intervention_or_exposure": "not extracted", "population": "not extracted", "risk_of_bias": "not appraised in public sidecar", "study": "Hyperbaric oxygen therapy effectively alleviates D-galactose-induced-age-related cardiac dysfunction via attenuating mitochondrial dysfunction in pre-diabetic rats", "type": "source", "url": null, "year": 2021}], "publication_id": "cfff5e6e-2337-4f55-95c8-b363344db16a", "screening": {"excluded": 0, "exclusion_reasons": ["No PRISMA full-text exclusion-stage filter was applied."], "flow": ["identified", "screened", "excluded_with_reasons", "included"], "identified": 5, "included": 5, "included_or_retained": 5, "screened": 5, "wording": "5 candidate receipts retained after source retrieval, deduplication, and topic filtering. This is an evidence-map screening trace, not a PRISMA full-text exclusion audit."}}

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