Derivation Web · source_2f324b7e482a4622

source · application/json

source_2f324b7e482a4622

sha256 fbac4460343b66a85e1aec1c56669e2c502bce03844fab32437397ed14e344ab

by researka:v2 · 2026-06-28 08:20:34.418448+04:00

{"publication_id": "21652f17-8a22-4863-aa37-ec5f4e1a7b90", "traces": [{"candidate_sources": [{"directness": "review-level", "doi": "10.1186/s12883-026-04780-1", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_1", "study": "Clinical and economic outcomes of therapeutic plasma exchange and intravenous immunoglobulin for treating adults with autoimmune neurological disorders: a systematic review and meta-analysis", "support_kind": "candidate_source_row", "url": "https://doi.org/10.1186/s12883-026-04780-1"}, {"directness": "primary", "doi": "10.1002/alz.12137", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_2", "study": "A randomized, controlled clinical trial of plasma exchange with albumin replacement for Alzheimer's disease: Primary results of the AMBAR Study", "support_kind": "candidate_source_row", "url": "https://doi.org/10.1002/alz.12137"}, {"directness": "review-level", "doi": "10.3389/fneur.2021.662856", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_3", "study": "Therapeutic Plasma Exchange in Myasthenia Gravis: A Systematic Literature Review and Meta-Analysis of Comparative Evidence", "support_kind": "candidate_source_row", "url": "https://doi.org/10.3389/fneur.2021.662856"}, {"directness": "review-level", "doi": "10.1002/alz.12477", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_4", "study": "Neuropsychological, neuropsychiatric, and quality‐of‐life assessments in Alzheimer's disease patients treated with plasma exchange with albumin replacement from the randomized AMBAR study", "support_kind": "candidate_source_row", "url": "https://doi.org/10.1002/alz.12477"}, {"directness": "primary", "doi": "10.3390/children12111457", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_5", "study": "Complications of Therapeutic Plasma Exchange in Pediatric Neuroimmune Disorders", "support_kind": "candidate_source_row", "url": "https://doi.org/10.3390/children12111457"}], "claim": "This paper synthesizes evidence on Therapeutic plasma exchange across 28 accepted source papers and 1449 high-confidence extracted claims.", "claim_id": "claim_1"}, {"candidate_sources": [{"directness": "review-level", "doi": "10.1186/s12883-026-04780-1", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_1", "study": "Clinical and economic outcomes of therapeutic plasma exchange and intravenous immunoglobulin for treating adults with autoimmune neurological disorders: a systematic review and meta-analysis", "support_kind": "candidate_source_row", "url": "https://doi.org/10.1186/s12883-026-04780-1"}, {"directness": "primary", "doi": "10.1002/alz.12137", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_2", "study": "A randomized, controlled clinical trial of plasma exchange with albumin replacement for Alzheimer's disease: Primary results of the AMBAR Study", "support_kind": "candidate_source_row", "url": "https://doi.org/10.1002/alz.12137"}, {"directness": "review-level", "doi": "10.3389/fneur.2021.662856", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_3", "study": "Therapeutic Plasma Exchange in Myasthenia Gravis: A Systematic Literature Review and Meta-Analysis of Comparative Evidence", "support_kind": "candidate_source_row", "url": "https://doi.org/10.3389/fneur.2021.662856"}, {"directness": "review-level", "doi": "10.1002/alz.12477", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_4", "study": "Neuropsychological, neuropsychiatric, and quality‐of‐life assessments in Alzheimer's disease patients treated with plasma exchange with albumin replacement from the randomized AMBAR study", "support_kind": "candidate_source_row", "url": "https://doi.org/10.1002/alz.12477"}, {"directness": "primary", "doi": "10.3390/children12111457", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_5", "study": "Complications of Therapeutic Plasma Exchange in Pediatric Neuroimmune Disorders", "support_kind": "candidate_source_row", "url": "https://doi.org/10.3390/children12111457"}], "claim": "The evidence profile contains 4 direct clinical sources, 24 adjacent clinical sources, and no sources classified primarily as mechanistic or model-system evidence, with a high-density pairwise disagreement map across the evidence base.", "claim_id": "claim_2"}, {"candidate_sources": [{"directness": "review-level", "doi": "10.1186/s12883-026-04780-1", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_1", "study": "Clinical and economic outcomes of therapeutic plasma exchange and intravenous immunoglobulin for treating adults with autoimmune neurological disorders: a systematic review and meta-analysis", "support_kind": "candidate_source_row", "url": "https://doi.org/10.1186/s12883-026-04780-1"}, {"directness": "primary", "doi": "10.1002/alz.12137", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_2", "study": "A randomized, controlled clinical trial of plasma exchange with albumin replacement for Alzheimer's disease: Primary results of the AMBAR Study", "support_kind": "candidate_source_row", "url": "https://doi.org/10.1002/alz.12137"}, {"directness": "review-level", "doi": "10.3389/fneur.2021.662856", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_3", "study": "Therapeutic Plasma Exchange in Myasthenia Gravis: A Systematic Literature Review and Meta-Analysis of Comparative Evidence", "support_kind": "candidate_source_row", "url": "https://doi.org/10.3389/fneur.2021.662856"}, {"directness": "review-level", "doi": "10.1002/alz.12477", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_4", "study": "Neuropsychological, neuropsychiatric, and quality‐of‐life assessments in Alzheimer's disease patients treated with plasma exchange with albumin replacement from the randomized AMBAR study", "support_kind": "candidate_source_row", "url": "https://doi.org/10.1002/alz.12477"}, {"directness": "primary", "doi": "10.3390/children12111457", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_5", "study": "Complications of Therapeutic Plasma Exchange in Pediatric Neuroimmune Disorders", "support_kind": "candidate_source_row", "url": "https://doi.org/10.3390/children12111457"}], "claim": "No single positive outcome class dominates the retained corpus; null signals cluster in the contextual adjacent evidence, immune and inflammation, safety and comorbidity outcome classes, and negative signals cluster in the contextual adjacent evidence outcome class. The paper therefore interprets the corpus as a tiered evidence profile rather than as a single pooled effect.", "claim_id": "claim_3"}, {"candidate_sources": [{"directness": "review-level", "doi": "10.1186/s12883-026-04780-1", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_1", "study": "Clinical and economic outcomes of therapeutic plasma exchange and intravenous immunoglobulin for treating adults with autoimmune neurological disorders: a systematic review and meta-analysis", "support_kind": "candidate_source_row", "url": "https://doi.org/10.1186/s12883-026-04780-1"}, {"directness": "primary", "doi": "10.1002/alz.12137", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_2", "study": "A randomized, controlled clinical trial of plasma exchange with albumin replacement for Alzheimer's disease: Primary results of the AMBAR Study", "support_kind": "candidate_source_row", "url": "https://doi.org/10.1002/alz.12137"}, {"directness": "review-level", "doi": "10.3389/fneur.2021.662856", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_3", "study": "Therapeutic Plasma Exchange in Myasthenia Gravis: A Systematic Literature Review and Meta-Analysis of Comparative Evidence", "support_kind": "candidate_source_row", "url": "https://doi.org/10.3389/fneur.2021.662856"}, {"directness": "review-level", "doi": "10.1002/alz.12477", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_4", "study": "Neuropsychological, neuropsychiatric, and quality‐of‐life assessments in Alzheimer's disease patients treated with plasma exchange with albumin replacement from the randomized AMBAR study", "support_kind": "candidate_source_row", "url": "https://doi.org/10.1002/alz.12477"}, {"directness": "primary", "doi": "10.3390/children12111457", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_5", "study": "Complications of Therapeutic Plasma Exchange in Pediatric Neuroimmune Disorders", "support_kind": "candidate_source_row", "url": "https://doi.org/10.3390/children12111457"}], "claim": "The conclusion is that Therapeutic plasma exchange remains a bounded geroscience case: the retained clinical and adjacent evidence profile defines the scope for targeted testing, while mixed and null findings limit any unqualified anti-aging claim.", "claim_id": "claim_4"}, {"candidate_sources": [{"directness": "review-level", "doi": "10.1186/s12883-026-04780-1", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_1", "study": "Clinical and economic outcomes of therapeutic plasma exchange and intravenous immunoglobulin for treating adults with autoimmune neurological disorders: a systematic review and meta-analysis", "support_kind": "candidate_source_row", "url": "https://doi.org/10.1186/s12883-026-04780-1"}, {"directness": "primary", "doi": "10.1002/alz.12137", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_2", "study": "A randomized, controlled clinical trial of plasma exchange with albumin replacement for Alzheimer's disease: Primary results of the AMBAR Study", "support_kind": "candidate_source_row", "url": "https://doi.org/10.1002/alz.12137"}, {"directness": "review-level", "doi": "10.3389/fneur.2021.662856", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_3", "study": "Therapeutic Plasma Exchange in Myasthenia Gravis: A Systematic Literature Review and Meta-Analysis of Comparative Evidence", "support_kind": "candidate_source_row", "url": "https://doi.org/10.3389/fneur.2021.662856"}, {"directness": "review-level", "doi": "10.1002/alz.12477", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_4", "study": "Neuropsychological, neuropsychiatric, and quality‐of‐life assessments in Alzheimer's disease patients treated with plasma exchange with albumin replacement from the randomized AMBAR study", "support_kind": "candidate_source_row", "url": "https://doi.org/10.1002/alz.12477"}, {"directness": "primary", "doi": "10.3390/children12111457", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_5", "study": "Complications of Therapeutic Plasma Exchange in Pediatric Neuroimmune Disorders", "support_kind": "candidate_source_row", "url": "https://doi.org/10.3390/children12111457"}], "claim": "This manuscript is reported as a Thin-corpus evidence brief. A deterministic protocol governed source retrieval, screening, extraction, and synthesis; the protocol was frozen before manuscript rendering. The full audit trail is in the supplementary `methods_pack.json` and the timestamped submission directory `synthesis-therapeutic_plasma_exchange-v06-DAILY-2026-06-28T04-15-17Z`.", "claim_id": "claim_5"}, {"candidate_sources": [{"directness": "review-level", "doi": "10.1186/s12883-026-04780-1", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_1", "study": "Clinical and economic outcomes of therapeutic plasma exchange and intravenous immunoglobulin for treating adults with autoimmune neurological disorders: a systematic review and meta-analysis", "support_kind": "candidate_source_row", "url": "https://doi.org/10.1186/s12883-026-04780-1"}, {"directness": "primary", "doi": "10.1002/alz.12137", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_2", "study": "A randomized, controlled clinical trial of plasma exchange with albumin replacement for Alzheimer's disease: Primary results of the AMBAR Study", "support_kind": "candidate_source_row", "url": "https://doi.org/10.1002/alz.12137"}, {"directness": "review-level", "doi": "10.3389/fneur.2021.662856", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_3", "study": "Therapeutic Plasma Exchange in Myasthenia Gravis: A Systematic Literature Review and Meta-Analysis of Comparative Evidence", "support_kind": "candidate_source_row", "url": "https://doi.org/10.3389/fneur.2021.662856"}, {"directness": "review-level", "doi": "10.1002/alz.12477", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_4", "study": "Neuropsychological, neuropsychiatric, and quality‐of‐life assessments in Alzheimer's disease patients treated with plasma exchange with albumin replacement from the randomized AMBAR study", "support_kind": "candidate_source_row", "url": "https://doi.org/10.1002/alz.12477"}, {"directness": "primary", "doi": "10.3390/children12111457", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_5", "study": "Complications of Therapeutic Plasma Exchange in Pediatric Neuroimmune Disorders", "support_kind": "candidate_source_row", "url": "https://doi.org/10.3390/children12111457"}], "claim": "The following fields were extracted from each included source: study design, population / cohort, intervention or exposure, comparator, outcome class, effect direction, effect size, confidence interval or credible interval, p-value, sample size, follow-up duration, risk-of-bias rating. Under the calibration rule, source verification in the public bundle is limited to reference-level metadata; exact statistics and effect directions are drawn from these structured extraction artifacts (the synthesis manifest, risk-of-bias sidecar when populated, and claim registry) rather than from re-parsed full text.", "claim_id": "claim_6"}, {"candidate_sources": [{"directness": "review-level", "doi": "10.1186/s12883-026-04780-1", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_1", "study": "Clinical and economic outcomes of therapeutic plasma exchange and intravenous immunoglobulin for treating adults with autoimmune neurological disorders: a systematic review and meta-analysis", "support_kind": "candidate_source_row", "url": "https://doi.org/10.1186/s12883-026-04780-1"}, {"directness": "primary", "doi": "10.1002/alz.12137", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_2", "study": "A randomized, controlled clinical trial of plasma exchange with albumin replacement for Alzheimer's disease: Primary results of the AMBAR Study", "support_kind": "candidate_source_row", "url": "https://doi.org/10.1002/alz.12137"}, {"directness": "review-level", "doi": "10.3389/fneur.2021.662856", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_3", "study": "Therapeutic Plasma Exchange in Myasthenia Gravis: A Systematic Literature Review and Meta-Analysis of Comparative Evidence", "support_kind": "candidate_source_row", "url": "https://doi.org/10.3389/fneur.2021.662856"}, {"directness": "review-level", "doi": "10.1002/alz.12477", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_4", "study": "Neuropsychological, neuropsychiatric, and quality‐of‐life assessments in Alzheimer's disease patients treated with plasma exchange with albumin replacement from the randomized AMBAR study", "support_kind": "candidate_source_row", "url": "https://doi.org/10.1002/alz.12477"}, {"directness": "primary", "doi": "10.3390/children12111457", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_5", "study": "Complications of Therapeutic Plasma Exchange in Pediatric Neuroimmune Disorders", "support_kind": "candidate_source_row", "url": "https://doi.org/10.3390/children12111457"}], "claim": "Risk-of-bias framework assignment follows study design (RoB-2 for RCTs, ROBINS-I for non-randomised studies, AMSTAR-2 for systematic reviews / meta-analyses). Public appraisal claims are limited to populated `risk_of_bias.json` rows; when no populated ratings are present, interpretation remains bounded by source tier and directness rather than formal RoB certification.", "claim_id": "claim_7"}, {"candidate_sources": [{"directness": "review-level", "doi": "10.1186/s12883-026-04780-1", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_1", "study": "Clinical and economic outcomes of therapeutic plasma exchange and intravenous immunoglobulin for treating adults with autoimmune neurological disorders: a systematic review and meta-analysis", "support_kind": "candidate_source_row", "url": "https://doi.org/10.1186/s12883-026-04780-1"}, {"directness": "primary", "doi": "10.1002/alz.12137", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_2", "study": "A randomized, controlled clinical trial of plasma exchange with albumin replacement for Alzheimer's disease: Primary results of the AMBAR Study", "support_kind": "candidate_source_row", "url": "https://doi.org/10.1002/alz.12137"}, {"directness": "review-level", "doi": "10.3389/fneur.2021.662856", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_3", "study": "Therapeutic Plasma Exchange in Myasthenia Gravis: A Systematic Literature Review and Meta-Analysis of Comparative Evidence", "support_kind": "candidate_source_row", "url": "https://doi.org/10.3389/fneur.2021.662856"}, {"directness": "review-level", "doi": "10.1002/alz.12477", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_4", "study": "Neuropsychological, neuropsychiatric, and quality‐of‐life assessments in Alzheimer's disease patients treated with plasma exchange with albumin replacement from the randomized AMBAR study", "support_kind": "candidate_source_row", "url": "https://doi.org/10.1002/alz.12477"}, {"directness": "primary", "doi": "10.3390/children12111457", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_5", "study": "Complications of Therapeutic Plasma Exchange in Pediatric Neuroimmune Disorders", "support_kind": "candidate_source_row", "url": "https://doi.org/10.3390/children12111457"}], "claim": "Evidence-tension synthesis: claims grouped by outcome class (contextual adjacent evidence, dosing and pharmacokinetics, immune and inflammation, longevity, mortality and survival, safety and comorbidity); within-class agreement, disagreement, and directness gaps surfaced explicitly. Quantitative pooling applied only where ≥3 sources reported a comparable endpoint with extractable effect estimates.", "claim_id": "claim_8"}, {"candidate_sources": [{"directness": "review-level", "doi": "10.1186/s12883-026-04780-1", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_1", "study": "Clinical and economic outcomes of therapeutic plasma exchange and intravenous immunoglobulin for treating adults with autoimmune neurological disorders: a systematic review and meta-analysis", "support_kind": "candidate_source_row", "url": "https://doi.org/10.1186/s12883-026-04780-1"}, {"directness": "primary", "doi": "10.1002/alz.12137", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_2", "study": "A randomized, controlled clinical trial of plasma exchange with albumin replacement for Alzheimer's disease: Primary results of the AMBAR Study", "support_kind": "candidate_source_row", "url": "https://doi.org/10.1002/alz.12137"}, {"directness": "review-level", "doi": "10.3389/fneur.2021.662856", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_3", "study": "Therapeutic Plasma Exchange in Myasthenia Gravis: A Systematic Literature Review and Meta-Analysis of Comparative Evidence", "support_kind": "candidate_source_row", "url": "https://doi.org/10.3389/fneur.2021.662856"}, {"directness": "review-level", "doi": "10.1002/alz.12477", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_4", "study": "Neuropsychological, neuropsychiatric, and quality‐of‐life assessments in Alzheimer's disease patients treated with plasma exchange with albumin replacement from the randomized AMBAR study", "support_kind": "candidate_source_row", "url": "https://doi.org/10.1002/alz.12477"}, {"directness": "primary", "doi": "10.3390/children12111457", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_5", "study": "Complications of Therapeutic Plasma Exchange in Pediatric Neuroimmune Disorders", "support_kind": "candidate_source_row", "url": "https://doi.org/10.3390/children12111457"}], "claim": "Source retrieval, claim extraction, evidence routing, and prose drafting were assisted by large language models under a deterministic audit-trail protocol. Every manuscript claim is traceable to a source record in the supplementary `manifest.json`. Final eligibility and interpretation decisions are author-verified.", "claim_id": "claim_9"}, {"candidate_sources": [{"directness": "review-level", "doi": "10.1186/s12883-026-04780-1", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_1", "study": "Clinical and economic outcomes of therapeutic plasma exchange and intravenous immunoglobulin for treating adults with autoimmune neurological disorders: a systematic review and meta-analysis", "support_kind": "candidate_source_row", "url": "https://doi.org/10.1186/s12883-026-04780-1"}, {"directness": "primary", "doi": "10.1002/alz.12137", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_2", "study": "A randomized, controlled clinical trial of plasma exchange with albumin replacement for Alzheimer's disease: Primary results of the AMBAR Study", "support_kind": "candidate_source_row", "url": "https://doi.org/10.1002/alz.12137"}, {"directness": "review-level", "doi": "10.3389/fneur.2021.662856", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_3", "study": "Therapeutic Plasma Exchange in Myasthenia Gravis: A Systematic Literature Review and Meta-Analysis of Comparative Evidence", "support_kind": "candidate_source_row", "url": "https://doi.org/10.3389/fneur.2021.662856"}, {"directness": "review-level", "doi": "10.1002/alz.12477", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_4", "study": "Neuropsychological, neuropsychiatric, and quality‐of‐life assessments in Alzheimer's disease patients treated with plasma exchange with albumin replacement from the randomized AMBAR study", "support_kind": "candidate_source_row", "url": "https://doi.org/10.1002/alz.12477"}, {"directness": "primary", "doi": "10.3390/children12111457", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_5", "study": "Complications of Therapeutic Plasma Exchange in Pediatric Neuroimmune Disorders", "support_kind": "candidate_source_row", "url": "https://doi.org/10.3390/children12111457"}], "claim": "Scope-framing note: This evidence map frames Therapeutic plasma exchange as clinical applications across heterogeneous indications rather than as standalone anti-aging or longevity proof. Aging-relevant interpretation is restricted to source rows whose endpoint, population, and outcome-class metadata directly support it; otherwise the retained evidence is contextual and hypothesis-generating.", "claim_id": "claim_10"}, {"candidate_sources": [{"directness": "review-level", "doi": "10.1186/s12883-026-04780-1", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_1", "study": "Clinical and economic outcomes of therapeutic plasma exchange and intravenous immunoglobulin for treating adults with autoimmune neurological disorders: a systematic review and meta-analysis", "support_kind": "candidate_source_row", "url": "https://doi.org/10.1186/s12883-026-04780-1"}, {"directness": "primary", "doi": "10.1002/alz.12137", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_2", "study": "A randomized, controlled clinical trial of plasma exchange with albumin replacement for Alzheimer's disease: Primary results of the AMBAR Study", "support_kind": "candidate_source_row", "url": "https://doi.org/10.1002/alz.12137"}, {"directness": "review-level", "doi": "10.3389/fneur.2021.662856", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_3", "study": "Therapeutic Plasma Exchange in Myasthenia Gravis: A Systematic Literature Review and Meta-Analysis of Comparative Evidence", "support_kind": "candidate_source_row", "url": "https://doi.org/10.3389/fneur.2021.662856"}, {"directness": "review-level", "doi": "10.1002/alz.12477", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_4", "study": "Neuropsychological, neuropsychiatric, and quality‐of‐life assessments in Alzheimer's disease patients treated with plasma exchange with albumin replacement from the randomized AMBAR study", "support_kind": "candidate_source_row", "url": "https://doi.org/10.1002/alz.12477"}, {"directness": "primary", "doi": "10.3390/children12111457", "effect": "not extracted", "endpoint": "not extracted", "population": "not extracted", "source_id": "source_5", "study": "Complications of Therapeutic Plasma Exchange in Pediatric Neuroimmune Disorders", "support_kind": "candidate_source_row", "url": "https://doi.org/10.3390/children12111457"}], "claim": "Boada 2020: A randomized, controlled clinical trial of plasma exchange with albumin replacement for Alzheimer's disease: Primary results of the AMBAR Study: outcome=Contextual Adjacent Evidence; 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