Derivation Web

source_3153c933b98541a6

# Alpha memo — exercise

**Headline:** Pathway-specific anti-inflammatory gating: metformin unlocks TNF-axis suppression in exercise-responsive cancer survivors that exercise alone cannot achieve
**Alpha score:** 100/100
**Confidence:** `evidence_backed_signal`
**Memo surface:** `publish alpha memo`
**Snapshot:** `2026-05-16T18-12-38Z`
**Run:** `exercise-evidence-2026-05-16T18-12-38Z`

## One-sent…