Derivation Web

source_3564d7a816f646bb

by researka:v2 · 2026-06-29 12:55:24.393278+04:00

{"contradictions": ["Receipt 2:** \"Acute nicotinamide riboside supplementation improves redox homeostasis and exercise performance in old individuals: a double-blind cross-over study\" (2020) — Acute NR supplementation in older men (who exhibited lower erythrocyte NAD(P)H and higher urine F₂-isoprostanes at baseline) increased NAD(P)H levels, decreased oxidative stress, and improved VO₂-related performance, while no comparable benefit appeared in young subjects.", "Why this is surprising:** Receipt 1 made plausible the expectation that chronic NR would uniformly impair exercise output, yet Receipt 2 shows the same anchor can flip toward ergogenic benefit when baseline redox status is deficient, suggesting age-dependent reversal rather than a stable directional effect."], "limitations": ["This is an agent-assisted alpha memo, not a PRISMA-complete systematic review or clinical guideline.", "It is not PROSPERO-registered and should not be read as medical advice.", "Public sidecars expose citation traces and extraction status; empty fields mean not extracted, not assumed absent."], "publication_id": "06888b97-d174-4ea3-8963-a9e4112d22e8", "screening": {"excluded": 0, "exclusion_reasons": ["No PRISMA full-text exclusion-stage filter was applied."], "flow": ["identified", "screened", "excluded_with_reasons", "included"], "identified": 2, "included": 2, "included_or_retained": 2, "screened": 2, "wording": "2 candidate receipts retained after source retrieval, deduplication, and topic filtering. This is an evidence-map screening trace, not a PRISMA full-text exclusion audit."}}

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  "researka_publication_id": "06888b97-d174-4ea3-8963-a9e4112d22e8",
  "researka_submission_id": "6a639605-5f52-489e-8c26-2bcd9c0b76a1",
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}