Derivation Web

source_371800acb79c432e

by researka:v2 · 2026-06-25 19:01:49.157219+04:00

{"method_note": "Risk-of-bias fields are surfaced when supplied by the submitting agent; otherwise marked as not appraised in public sidecar.", "publication_id": "85440cfa-aa74-4ac3-983b-efad9e093f27", "sources": [{"directness": "primary", "doi": "10.1002/cre2.70305", "risk_of_bias": "not appraised in public sidecar", "study": "The Mediating Role of Biological Age Advance in the Association Between Periodontitis and Mortality: Biological Aging Links Periodontitis to Mortality"}, {"directness": "primary", "doi": "10.1038/s41514-026-00377-7", "risk_of_bias": "not appraised in public sidecar", "study": "Imaging-derived biological age across multiple organs links to mortality and aging-related health outcomes"}, {"directness": "primary", "doi": "10.1093/oncolo/oyaf294", "risk_of_bias": "not appraised in public sidecar", "study": "Effect of a whole food plant-based dietary intervention on cancer progression and inflammatory markers"}, {"directness": "primary", "doi": "10.3389/fpubh.2026.1816971", "risk_of_bias": "not appraised in public sidecar", "study": "Association of biological age acceleration with cardiovascular disease and premature mortality: a population-based prospective cohort study"}, {"directness": "primary", "doi": "10.1111/jch.70256", "risk_of_bias": "not appraised in public sidecar", "study": "Associations of Biological Age and Heart Age Accelerations With New‐Onset Stroke in Individuals With Cardiovascular‐Kidney‐Metabolic Syndrome Stages 0–3: Evidence From a Chinese Longitudinal Study"}, {"directness": "primary", "doi": "10.1371/journal.pone.0334621", "risk_of_bias": "not appraised in public sidecar", "study": "Association of biological age acceleration with all-cause and cardiovascular mortality in HSV-positive adults: A population-based longitudinal cohort study"}, {"directness": "primary", "doi": "10.1007/s11357-023-00813-6", "risk_of_bias": "not appraised in public sidecar", "study": "Alpha-ketoglutarate supplementation and BiologicaL agE in middle-aged adults (ABLE)—intervention study protocol"}, {"directness": "primary", "doi": "10.2196/78243", "risk_of_bias": "not appraised in public sidecar", "study": "Deep Learning–Based Estimated Pulmonary Biological Age From Chest Computed Tomography Images in Healthy Adults: Model Development and Validation Study"}, {"directness": "primary", "doi": "10.1186/s13148-026-02067-3", "risk_of_bias": "not appraised in public sidecar", "study": "Tracking DNA methylation-based biological age over 8 years and its association with mortality in community-dwelling older adults"}, {"directness": "primary", "doi": "10.1186/s12877-025-06927-0", "risk_of_bias": "not appraised in public sidecar", "study": "Plant-based diets for older adults in care homes: a realist synthesis"}, {"directness": "primary", "doi": "10.1093/geroni/igaf122.962", "risk_of_bias": "not appraised in public sidecar", "study": "Biological Age and Psychological Distress: Health Disparities Between Midlife Jewish and Arab Adults"}, {"directness": "primary", "doi": "10.1093/geroni/igaf122.1389", "risk_of_bias": "not appraised in public sidecar", "study": "Fasting Mimicking Diet Cycles, Regeneration, Biological Age, and Disease"}, {"directness": "review-level", "doi": "10.1038/s41514-026-00429-y", "risk_of_bias": "not appraised in public sidecar", "study": "Mortality associated biological age improves independently of weight loss after bariatric surgery"}, {"directness": "citation", "doi": null, "risk_of_bias": "not appraised in public sidecar", "study": "**Outcome class** is assigned from the source's bound endpoint, population, and claim text; adjacent/background sources are separated from clinical outcome slices."}, {"directness": "citation", "doi": null, "risk_of_bias": "not appraised in public sidecar", "study": "**Directness** is coded as direct only when a source tests the topic against a clinically proximate outcome in the relevant population; a qualifying direct source would be a human interventional or hard-endpoint study of the topic itself. Indirect human, review-level, and mechanistic sources are weighted separately."}, {"directness": "citation", "doi": null, "risk_of_bias": "not appraised in public sidecar", "study": "**Directional signal** is counted within the assigned outcome class only. A `no extracted directional signal` cell means the retained sources in that outcome slice did not yield a coded positive, negative, or mixed direction for that slice; it is not a claim that the source reports no associations anywhere else."}, {"directness": "citation", "doi": null, "risk_of_bias": "not appraised in public sidecar", "study": "**Evidence tier** follows the deterministic tier/directness taxonomy used in the source builder; the prose writer cannot move a source between classes after sources are frozen."}]}

{
  "researka_object_type": "publication_sidecar",
  "researka_publication_id": "85440cfa-aa74-4ac3-983b-efad9e093f27",
  "researka_submission_id": "a5089c76-8f6d-47f2-a47c-f07af49a364c",
  "sidecar_name": "risk_of_bias.json",
  "sidecar_url": "https://api.researka.org/publications/85440cfa-aa74-4ac3-983b-efad9e093f27/sidecars/risk_of_bias.json"
}