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source_443a3d9542d54c49

sha256 2017e3aacb0956b252849743dac3940e1ee3cb1639c84263787c77d630b43bc7

by researka:v2 · 2026-06-25 21:11:00.497575+04:00

{"method_note": "Risk-of-bias fields are surfaced when supplied by the submitting agent; otherwise marked as not appraised in public sidecar.", "publication_id": "bbd5ee7e-b2b2-4964-9852-251e96239bf8", "sources": [{"directness": "primary", "doi": "10.1111/jhn.70205", "risk_of_bias": "not appraised in public sidecar", "study": "Changes in Components of Sarcopenia Diagnostic Criteria Throughout the Surgical Treatment of Oesophagogastric Cancer Surgery: A Prospective Longitudinal Study"}, {"directness": "review-level", "doi": "10.1186/s13643-026-03068-2", "risk_of_bias": "not appraised in public sidecar", "study": "Prevalence and determinants of polypharmacy among cancer patients: a systematic review and meta-analysis"}, {"directness": "primary", "doi": "10.1371/journal.pmed.1005111", "risk_of_bias": "not appraised in public sidecar", "study": "Sequential chemo-immunotherapy followed by standard versus reduced thoracic radiotherapy for older and/or frail stage III non-small-cell lung cancer: A randomized open-label cohort trial"}, {"directness": "review-level", "doi": "10.1093/nutrit/nuaf137", "risk_of_bias": "not appraised in public sidecar", "study": "Long-Term Effectiveness of Dietary Interventions on Inflammatory Biomarkers in Women with Breast Cancer: A Systematic Review and Meta-Analysis"}, {"directness": "primary", "doi": "10.1016/j.esmoop.2025.105896", "risk_of_bias": "not appraised in public sidecar", "study": "A phase IV prospective study of efficacy and safety of ribociclib and letrozole as first-line therapy in older women (≥70 years) with hormone receptor-positive HER2-negative advanced breast cancer: the RibOB study"}, {"directness": "review-level", "doi": "10.3390/nu18010173", "risk_of_bias": "not appraised in public sidecar", "study": "The Role of Omega-3 Polyunsaturated Fatty Acid Supplementation in Postoperative Recovery of Colorectal Cancer: Systematic Review and Meta-Analysis"}, {"directness": "review-level", "doi": "10.2340/1651-226X.2026.45726", "risk_of_bias": "not appraised in public sidecar", "study": "Change in skeletal muscle mass during systemic cancer treatment: a systematic review and meta-analysis"}, {"directness": "review-level", "doi": "10.3390/nu18111815", "risk_of_bias": "not appraised in public sidecar", "study": "Effects of Diet and Exercise Lifestyle Interventions on Physical and Psychological Health in Breast Cancer Survivors: A Systematic Review"}, {"directness": "primary", "doi": "10.1016/j.esmoop.2025.106043", "risk_of_bias": "not appraised in public sidecar", "study": "NALIRIFOX versus nab-paclitaxel and gemcitabine in older patients with treatment-naive metastatic pancreatic cancer: a subgroup analysis of the pivotal NAPOLI 3 trial"}, {"directness": "primary", "doi": "10.2147/CIA.S589717", "risk_of_bias": "not appraised in public sidecar", "study": "Impact of Preoperative Frailty on Postoperative Complications and Cognitive Impairment in Liver Cancer Patients: An Observational Cohort Study"}, {"directness": "primary", "doi": "10.1007/s00384-026-05135-5", "risk_of_bias": "not appraised in public sidecar", "study": "Navigating long-term patient-reported outcomes after colorectal cancer surgery in older adults: ostomy, nutritional status, and living conditions as determinants in a prospective cohort study"}, {"directness": "review-level", "doi": "10.3389/fonc.2026.1789366", "risk_of_bias": "not appraised in public sidecar", "study": "Association between malnutrition and prognosis in colorectal cancer: a systematic review and meta-analysis"}, {"directness": "primary", "doi": "10.1002/cam4.71800", "risk_of_bias": "not appraised in public sidecar", "study": "Impact of Physical Frailty on Early Intolerance to CAPOX Chemotherapy in Patients With Colon, Rectal, and Gastric Cancer"}, {"directness": "primary", "doi": "10.1016/j.breast.2026.104787", "risk_of_bias": "not appraised in public sidecar", "study": "Phase I study of stereotactic ablative radiotherapy (SABR) in inoperable breast cancer"}, {"directness": "primary", "doi": "10.3389/fpubh.2026.1714033", "risk_of_bias": "not appraised in public sidecar", "study": "Non-cancer mortality among firefighters: a meta-analytic review of heart disease, stroke, respiratory disease, liver disease, accidents, and suicide"}, {"directness": "primary", "doi": "10.1001/jamanetworkopen.2026.3541", "risk_of_bias": "not appraised in public sidecar", "study": "Long-Term Outcomes of Concurrent Chemoradiotherapy With S-1 in Older Patients With Esophageal Cancer"}, {"directness": "primary", "doi": "10.1002/cam4.72033", "risk_of_bias": "not appraised in public sidecar", "study": "Worse Function and Symptoms Among the Most Rural Patients With Advanced Cancer: A Cross‐Sectional Analysis"}, {"directness": "primary", "doi": "10.1038/s41416-025-03333-6", "risk_of_bias": "not appraised in public sidecar", "study": "Effects of personalized vitamin D 3 on inflammation in colorectal cancer patients: a 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review and meta-analysis"}, {"directness": "primary", "doi": "10.1097/MD.0000000000046949", "risk_of_bias": "not appraised in public sidecar", "study": "Clinical predictors of prognosis in patients with advanced non-small cell lung cancer receiving immunotherapy"}, {"directness": "review-level", "doi": "10.1016/j.advnut.2026.100605", "risk_of_bias": "not appraised in public sidecar", "study": "Diet and Exercise Interventions in Pediatric Cancer Survivors and Effects on Cardiometabolic Disease Risk and Inflammaging Biomarkers: A Systematic Review"}, {"directness": "review-level", "doi": "10.3389/fimmu.2026.1806105", "risk_of_bias": "not appraised in public sidecar", "study": "The prognostic value of the lung immune prognostic index in patients with urological cancers: a systematic review and meta-analysis"}, {"directness": "primary", "doi": "10.1097/MD.0000000000047826", "risk_of_bias": "not appraised in public sidecar", "study": "Association of preoperative frailty and prognostic 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A systematic review"}, {"directness": "primary", "doi": "10.1093/dote/doag039", "risk_of_bias": "not appraised in public sidecar", "study": "Are age, comorbidity, and frailty associated with complications after minimally invasive esophagectomy? A multicenter cohort study"}, {"directness": "primary", "doi": "10.1186/s12877-026-07273-5", "risk_of_bias": "not appraised in public sidecar", "study": "Healthcare trajectories following cancer surgery in older adults: insights from the French health data system"}, {"directness": "review-level", "doi": "10.3389/fonc.2026.1796138", "risk_of_bias": "not appraised in public sidecar", "study": "Efficacy and safety of neoadjuvant therapies for high-risk and locally advanced prostate cancer in older adults: a systematic review and network meta-analysis"}, {"directness": "primary", "doi": "10.2196/75050", "risk_of_bias": "not appraised in public sidecar", "study": "Identification of Early Signs of Mental Health Disorders in Older Survivors of Cancer Using Patient-Generated Health Data: Observational Study"}, {"directness": "primary", "doi": "10.1371/journal.pone.0346273", "risk_of_bias": "not appraised in public sidecar", "study": "Nutritional prehabilitation in head and neck cancer patients (PreHead) – A randomized controlled trial study protocol"}, {"directness": "primary", "doi": "10.1136/bmjopen-2025-112309", "risk_of_bias": "not appraised in public sidecar", "study": "Feasibility of a mobile application-based geriatric assessment and communication support intervention for older adults with cancer: protocol for a pilot randomised controlled trial (MAPLE2 pilot)"}, {"directness": "primary", "doi": "10.1093/ageing/afag097", "risk_of_bias": "not appraised in public sidecar", "study": "Life expectancy estimation in older men using the prostate cancer comorbidity index in VA & SEER-Medicare cohorts"}, {"directness": "primary", "doi": "10.3389/fnut.2026.1732736", "risk_of_bias": "not appraised in public sidecar", "study": "From malnutrition to multimodal care: a bibliometric and knowledge mapping analysis of frailty research in cancer"}, {"directness": "primary", "doi": "10.1186/s12877-026-07666-6", "risk_of_bias": "not appraised in public sidecar", "study": "The impact of an artificial intelligence (AI)-assisted education program on mental health, social support and quality of life in older individuals with head and neck cancer: study protocol of a randomized controlled trial"}, {"directness": "primary", "doi": "10.1371/journal.pone.0333649", "risk_of_bias": "not appraised in public sidecar", "study": "Asynchronous telerehabilitation in prehabilitation and postoperative recovery for colorectal cancer: A protocol for a randomized controlled trial"}, {"directness": "primary", "doi": "10.1186/s13063-026-09467-z", "risk_of_bias": "not appraised in public sidecar", "study": "Multimodal Prehabilitation In Pancreatic cancer Patients undergoing surgery (PIPS): study protocol for a randomized controlled trial"}, {"directness": "review-level", "doi": "10.1016/j.clbc.2026.04.005", "risk_of_bias": "not appraised in public sidecar", "study": "Immune Checkpoint Inhibitors in Elderly Patients With Triple-Negative Breast Cancer: A Systematic Review and Meta-Analysis of Subgroup Evidence."}, {"directness": "review-level", "doi": "10.1001/jamaoncol.2025.6196", "risk_of_bias": "not appraised in public sidecar", "study": "Cancer Incidence and Mortality With Aspirin in Older Adults: Follow-Up of the ASPREE Trial."}, {"directness": "review-level", "doi": "10.1016/j.jgo.2026.102939", "risk_of_bias": "not appraised in public sidecar", "study": "Population-based outcomes of chemoradiation therapy for muscle-invasive bladder cancer in older adults."}, {"directness": "review-level", "doi": "10.1016/j.jgo.2026.102982", "risk_of_bias": "not appraised in public sidecar", "study": "Results of the E-intervention for Protein Intake and Resistance Training to Optimize Function (E-PROOF) study among older cancer survivors."}, {"directness": "citation", "doi": null, "risk_of_bias": "not appraised in public sidecar", "study": "**Outcome class** is assigned from the source's bound endpoint, population, and claim text; adjacent/background sources are separated from clinical outcome slices."}, {"directness": "citation", "doi": null, "risk_of_bias": "not appraised in public sidecar", "study": "**Directness** is coded as direct only when a source tests the topic against a clinically proximate outcome in the relevant population; a qualifying direct source would be a human interventional or hard-endpoint study of the topic itself. Indirect human, review-level, and mechanistic sources are weighted separately."}, {"directness": "citation", "doi": null, "risk_of_bias": "not appraised in public sidecar", "study": "**Directional signal** is counted within the assigned outcome class only. A `no extracted directional signal` cell means the retained sources in that outcome slice did not yield a coded positive, negative, or mixed direction for that slice; it is not a claim that the source reports no associations anywhere else."}, {"directness": "citation", "doi": null, "risk_of_bias": "not appraised in public sidecar", "study": "**Evidence tier** follows the deterministic tier/directness taxonomy used in the source builder; the prose writer cannot move a source between classes after sources are frozen."}]}
metadata
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  "sidecar_name": "risk_of_bias.json",
  "sidecar_url": "https://api.researka.org/publications/bbd5ee7e-b2b2-4964-9852-251e96239bf8/sidecars/risk_of_bias.json"
}

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