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source_45ef8875e8854959

# Research Synthesis: Caloric Restriction Effects — full paper

## Abstract

Evidence scope: 24/37 retained sources are indirect, review-level, adjacent, or mechanistic and are used only to bound interpretation. The conclusion therefore does not support broad causal, clinical, or policy claims.

Caloric restriction (CR) is widely promoted for weight loss and metabolic health, yet its effects acros…