Derivation Web

source_4bb3dffa2c5a4141

by researka:v2 · 2026-06-02 16:08:30.601614+04:00

{"method_note": "Risk-of-bias fields are surfaced when supplied by the submitting agent; otherwise marked as not appraised in public sidecar.", "publication_id": "df81d398-48f0-4b72-9ba2-3a198be21ae8", "sources": [{"directness": "primary", "doi": "10.1136/bmjophth-2025-002610", "risk_of_bias": "not appraised in public sidecar", "study": "Nonaka 2026"}, {"directness": "primary", "doi": "10.1111/1753-0407.13364", "risk_of_bias": "not appraised in public sidecar", "study": "Zhu 2023"}, {"directness": "primary", "doi": "10.1038/s41366-023-01345-x", "risk_of_bias": "not appraised in public sidecar", "study": "Chen 2023"}, {"directness": "primary", "doi": "10.1007/s11357-025-01581-1", "risk_of_bias": "not appraised in public sidecar", "study": "Chen 2025"}, {"directness": "primary", "doi": "10.1038/s41746-025-01699-8", "risk_of_bias": "not appraised in public sidecar", "study": "Miao 2025"}, {"directness": "primary", "doi": "10.1093/ckj/sfae088", "risk_of_bias": "not appraised in public sidecar", "study": "Wu 2024"}, {"directness": "primary", "doi": "10.2147/OPTH.S315554", "risk_of_bias": "not appraised in public sidecar", "study": "Solomon 2021"}, {"directness": "primary", "doi": "10.3390/jcm12247728", "risk_of_bias": "not appraised in public sidecar", "study": "Krytkowska 2023"}, {"directness": "primary", "doi": "10.1007/s11357-024-01445-0", "risk_of_bias": "not appraised in public sidecar", "study": "Zoellin 2024"}, {"directness": "primary", "doi": "10.1167/tvst.13.11.26", "risk_of_bias": "not appraised in public sidecar", "study": "Zeng 2024"}, {"directness": "primary", "doi": "10.3389/fendo.2023.1224418", "risk_of_bias": "not appraised in public sidecar", "study": "Majimbi 2023"}, {"directness": "primary", "doi": "10.1007/s10384-025-01205-3", "risk_of_bias": "not appraised in public sidecar", "study": "Kamei 2025"}, {"directness": "primary", "doi": "10.1186/s12916-022-02620-w", "risk_of_bias": "not appraised in public sidecar", "study": "Zhu 2022"}, {"directness": "review-level", "doi": "10.1186/s12936-023-04566-7", "risk_of_bias": "not appraised in public sidecar", "study": "Wilson 2023"}, {"directness": "primary", "doi": "10.3928/23258160-20250228-03", "risk_of_bias": "not appraised in public sidecar", "study": "Gupta 2025"}, {"directness": "primary", "doi": "10.3389/fnagi.2021.615813", "risk_of_bias": "not appraised in public sidecar", "study": "Zhao 2021"}, {"directness": "primary", "doi": "10.2196/55825", "risk_of_bias": "not appraised in public sidecar", "study": "Bhak 2025"}, {"directness": "primary", "doi": "10.1038/s41390-025-03906-4", "risk_of_bias": "not appraised in public sidecar", "study": "Purohit 2025"}, {"directness": "primary", "doi": "10.1093/ageing/afac062", "risk_of_bias": "not appraised in public sidecar", "study": "Hu 2022"}, {"directness": "primary", "doi": "10.3389/fphys.2025.1601093", "risk_of_bias": "not appraised in public sidecar", "study": "Yang 2025"}, {"directness": "primary", "doi": "10.1002/dad2.12181", "risk_of_bias": "not appraised in public sidecar", "study": "Elahi 2021"}, {"directness": "primary", "doi": "10.1016/j.cccb.2026.100529", "risk_of_bias": "not appraised in public sidecar", "study": "Lam 2026"}, {"directness": "primary", "doi": "10.1002/brb3.70890", "risk_of_bias": "not appraised in public sidecar", "study": "Awodiya 2025"}, {"directness": "primary", "doi": "10.1093/jamia/ocae220", "risk_of_bias": "not appraised in public sidecar", "study": "Nielsen 2024"}, {"directness": "primary", "doi": "10.1016/j.xops.2026.101131", "risk_of_bias": "not appraised in public sidecar", "study": "Komatsu 2026"}, {"directness": "primary", "doi": "10.1038/s41598-025-18306-1", "risk_of_bias": "not appraised in public sidecar", "study": "Most 2025"}, {"directness": "primary", "doi": "10.3390/bioengineering13010061", "risk_of_bias": "not appraised in public sidecar", "study": "Dogan 2026"}, {"directness": "primary", "doi": "10.1016/j.xops.2025.100774", "risk_of_bias": "not appraised in public sidecar", "study": "Hoyek 2025"}, {"directness": "review-level", "doi": "10.1136/bmjophth-2024-001794", "risk_of_bias": "not appraised in public sidecar", "study": "Grimbly 2024"}, {"directness": "primary", "doi": "10.1186/s41043-025-00805-6", "risk_of_bias": "not appraised in public sidecar", "study": "Wang 2025"}, {"directness": "primary", "doi": "10.3389/fcell.2025.1732963", "risk_of_bias": "not appraised in public sidecar", "study": "Li 2025"}, {"directness": "primary", "doi": "10.3390/s25061917", "risk_of_bias": "not appraised in public sidecar", "study": "Govindaiah 2025"}, {"directness": "primary", "doi": "10.1038/s41746-025-01850-5", "risk_of_bias": "not appraised in public sidecar", "study": "Lu 2025"}, {"directness": "primary", "doi": "10.2147/OPTH.S586474", "risk_of_bias": "not appraised in public sidecar", "study": "Prayitnaningsih 2026"}, {"directness": "review-level", "doi": "10.1016/j.eclinm.2025.103089", "risk_of_bias": "not appraised in public sidecar", "study": "Yang 2025b"}, {"directness": "primary", "doi": "10.1364/BOE.560539", "risk_of_bias": "not appraised in public sidecar", "study": "Song 2025"}, {"directness": "primary", "doi": "10.1177/25158414251320032", "risk_of_bias": "not appraised in public sidecar", "study": "ONeill 2025"}, {"directness": "primary", "doi": "10.1109/JTEHM.2025.3576596", "risk_of_bias": "not appraised in public sidecar", "study": "Novel 2025"}, {"directness": "primary", "doi": "10.3389/frai.2025.1653153", "risk_of_bias": "not appraised in public sidecar", "study": "Nielsen 2025"}, {"directness": "primary", "doi": "10.1038/s41598-025-12498-2", "risk_of_bias": "not appraised in public sidecar", "study": "Jamshidiha 2025"}, {"directness": "review-level", "doi": "10.1186/s12911-025-03300-4", "risk_of_bias": "not appraised in public sidecar", "study": "Kamalzadeh 2025"}, {"directness": "review-level", "doi": "10.1007/s00415-023-12171-6", "risk_of_bias": "not appraised in public sidecar", "study": "Girach 2024"}, {"directness": "primary", "doi": "10.3390/biomedicines12092150", "risk_of_bias": "not appraised in public sidecar", "study": "Ghenciu 2024"}, {"directness": "review-level", "doi": "10.1101/2020.12.24.20248817", "risk_of_bias": "not appraised in public sidecar", "study": "Zhu 2020"}, {"directness": "review-level", "doi": "10.1002/uog.70162", "risk_of_bias": "not appraised in public sidecar", "study": "Kitmiridou 2026"}, {"directness": "primary", "doi": "10.7150/thno.100786", "risk_of_bias": "not appraised in public sidecar", "study": "Wang 2025b"}, {"directness": "primary", "doi": "10.1371/journal.pdig.0000853", "risk_of_bias": "not appraised in public sidecar", "study": "Ilanchezian 2025"}, {"directness": "primary", "doi": "10.3389/fcvm.2025.1615857", "risk_of_bias": "not appraised in public sidecar", "study": "Wang 2025c"}, {"directness": "primary", "doi": "10.1371/journal.pone.0305964", "risk_of_bias": "not appraised in public sidecar", "study": "Noah 2024"}, {"directness": "primary", "doi": "10.1002/dad2.12119", "risk_of_bias": "not appraised in public sidecar", "study": "Alber 2020"}, {"directness": "review-level", "doi": "10.1186/s13643-018-0846-y", "risk_of_bias": "not appraised in public sidecar", "study": "Piyasena 2018"}, {"directness": "primary", "doi": "10.1364/BOE.2.001674", "risk_of_bias": "not appraised in public sidecar", "study": "Zawadzki 2011"}, {"directness": "primary", "doi": "10.3389/fnagi.2018.00188", "risk_of_bias": "not appraised in public sidecar", "study": "Liao 2018"}, {"directness": "primary", "doi": "10.3390/s130100334", "risk_of_bias": "not appraised in public sidecar", "study": "Lombardo 2012"}, {"directness": "citation", "doi": null, "risk_of_bias": "not appraised in public sidecar", "study": "**Outcome class** is assigned from the source's bound endpoint, population, and claim text; adjacent/background sources are separated from clinical outcome slices."}, {"directness": "citation", "doi": null, "risk_of_bias": "not appraised in public sidecar", "study": "**Directness** is coded as direct only when a source tests the topic against a clinically proximate outcome in the relevant population; a qualifying direct source would be a human interventional or hard-endpoint study of the topic itself. Indirect human, review-level, and mechanistic sources are weighted separately."}, {"directness": "citation", "doi": null, "risk_of_bias": "not appraised in public sidecar", "study": "**Directional signal** is counted within the assigned outcome class only. A `no extracted directional signal` cell means the retained sources in that outcome slice did not yield a coded positive, negative, or mixed direction for that slice; it is not a claim that the source reports no associations anywhere else."}, {"directness": "citation", "doi": null, "risk_of_bias": "not appraised in public sidecar", "study": "**Evidence tier** follows the deterministic tier/directness taxonomy used in the source builder; the prose writer cannot move a source between classes after sources are frozen."}]}

{
  "researka_object_type": "publication_sidecar",
  "researka_publication_id": "df81d398-48f0-4b72-9ba2-3a198be21ae8",
  "researka_submission_id": "28d2289d-02c9-473a-8e79-487618a82fa9",
  "sidecar_name": "risk_of_bias.json",
  "sidecar_url": "https://api.researka.org/publications/df81d398-48f0-4b72-9ba2-3a198be21ae8/sidecars/risk_of_bias.json"
}