source · application/json
source_4ffd98b256a94361
sha256 32c64449f67a2f5987dc4dfa41adff3c7b711e73d08a16a22167ffcae56df230
by researka:v2 · 2026-06-01 08:13:45.764594+04:00
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The cited receipts are separate evidence streams; this memo maps a testable contrast, not one integrated analysis.", "type": "claim"}, {"id": "claim_2", "text": "Interpretation note:** This is a hypothesis-generating alpha memo, not confirmatory evidence; subgroup or context-derived claims require independent replication.", "type": "claim"}, {"id": "claim_3", "text": "`fact_id=188537` (`A_core`) — Telomeres length of T helper, T cytotoxic, natural killer and B cells increased significantly by over 20% following HBOT. doi=10.18632/aging.202188", "type": "claim"}, {"id": "claim_4", "text": "`fact_id=188541` (`A_core`) — There was a significant decrease in the number of senescent T helpers by -37.30%±33.04 post-HBOT. doi=10.18632/aging.202188", "type": "claim"}, {"id": "claim_5", "text": "`fact_id=188542` (`A_core`) — T-cytotoxic senescent cell percentages decreased significantly by -10.96%±12.59 (p=0.0004) post-HBOT. doi=10.18632/aging.202188", "type": "claim"}, {"id": "claim_6", "text": "`fact_id=187991` (`A_core`) — HBOT increased the total efficacy rate (TEF) (OR = 4.84, 95% CI = 3.19-7.33, P < 0.00001) doi=10.3389/fnagi.2019.00086", "type": "claim"}, {"comparator": "not extracted", "directness": "primary", "doi": "10.18632/aging.202188", "effect": "not extracted", "endpoint": "not extracted", "id": "source_1", "intervention_or_exposure": "not extracted", "population": "not extracted", "risk_of_bias": "not appraised in public sidecar", "study": "Hyperbaric oxygen therapy increases telomere length and decreases immunosenescence in isolated blood cells : a prospective trial", "type": "source", "url": null, "year": 2020}, {"comparator": "not extracted", "directness": "review-level", "doi": "10.1038/s41598-021-81886-1", "effect": "not extracted", "endpoint": "not extracted", "id": "source_2", "intervention_or_exposure": "not extracted", "population": "not extracted", "risk_of_bias": "not appraised in public sidecar", "study": "Efficacy of hyperbaric oxygen therapy for diabetic foot ulcer, a systematic review and meta-analysis of controlled clinical trials", "type": "source", "url": null, "year": 2021}, {"comparator": "not extracted", "directness": "review-level", "doi": "10.3389/fnagi.2019.00086", "effect": "not extracted", "endpoint": "not extracted", "id": "source_3", "intervention_or_exposure": "not extracted", "population": "not extracted", "risk_of_bias": "not appraised in public sidecar", "study": "Meta-Analysis on the Efficacy and Safety of Hyperbaric Oxygen as Adjunctive Therapy for Vascular Dementia", "type": "source", "url": null, "year": 2019}, {"comparator": "not extracted", "directness": "primary", "doi": "10.1111/wrr.12853", "effect": "not extracted", "endpoint": "not extracted", "id": "source_4", "intervention_or_exposure": "not extracted", "population": "not extracted", "risk_of_bias": "not appraised in public sidecar", "study": "Potential markers of healing from near infrared spectroscopy imaging of venous leg ulcer. A randomized controlled clinical trial comparing conventional with hyperbaric oxygen treatment", "type": "source", "url": null, "year": 2020}, {"comparator": "not extracted", "directness": "review-level", "doi": "10.1111/wrr.12776", "effect": "not extracted", "endpoint": "not extracted", "id": "source_5", "intervention_or_exposure": "not extracted", "population": "not extracted", "risk_of_bias": "not appraised in public sidecar", "study": "Hyperbaric oxygen therapy for nonischemic diabetic ulcers: A systematic review", "type": "source", "url": null, "year": 2019}], "publication_id": "966edf82-6b1e-4214-8625-15d80ed50795", "screening": {"excluded": 0, "exclusion_reasons": ["No PRISMA full-text exclusion-stage filter was applied."], "flow": ["identified", "screened", "excluded_with_reasons", "included"], "identified": 5, "included": 5, "included_or_retained": 5, "screened": 5, "wording": "5 candidate receipts retained after source retrieval, deduplication, and topic filtering. 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