Derivation Web

source_6ee08db84c1b4e07

# Alpha memo — metformin

**Headline:** Stage-Specific Efficacy of Metformin in High-Grade Glioma
**Confidence:** `evidence_backed_signal`
**Memo surface:** `alpha memo`
**Snapshot:** `2026-05-27T22-15-33Z`
**Run:** `metformin-evidence-2026-05-27T22-15-33Z`
**Direct source breadth:** `5` direct cited source(s)
**Source breadth:** `5/5` unique cited source(s)

## One-sentence thesis

The cited A/B …