Derivation Web

source_716ab484b88c4865

by researka:v2 · 2026-07-16 06:59:12.791061+04:00

study,population,intervention_or_exposure,comparator,endpoint,effect,risk_of_bias,directness
Impact of oral statin therapy on clinical outcomes in patients with cT1 breast cancer,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Efficacy and safety of lipid-lowering therapies in combination with or without statin to reduce the cardiovascular risk: A systematic review of randomised controlled trials,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
Reno-protective effects of statins among patients with chronic kidney disease in Hong Kong: a target trial emulation,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Lipid-Lowering Efficacy and Safety of a New Generic Rosuvastatin in Koreans: an 8-Week Randomized Comparative Study with a Proprietary Rosuvastatin,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Effects silymarin and rosuvastatin on amyloid-carriers level in dyslipidemic Alzheimer’s patients: A double-blind placebo-controlled randomized clinical trial,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Trends and outcome of statin therapy in dialysis patients with atherosclerotic cardiovascular diseases: A population-based cohort study,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
"The prognosis of lipid reprogramming with the HMG-CoA reductase inhibitor, rosuvastatin, in castrated Egyptian prostate cancer patients: Randomized trial",not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
The effect of rosuvastatin alone or in combination with fenofibrate or omega-3 fatty acids on lipoprotein(a) levels in patients with mixed hyperlipidemia,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Effects of Evolocumab Added to Moderate-Intensity Statin Therapy in Chinese Patients With Acute Coronary Syndrome: The EMSIACS Trial Study Protocol,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
"Financial resources, access to care, and quality of care mediate racial disparities in statin usage for secondary prevention",not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
"Influence of Statin Therapy on the Incidence of Cardiovascular Events, Cancer, and All-Cause Mortality in People Living With HIV: A Meta-Analysis",not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
"Candesartan, Metoprolol and Rosuvastatin Associated to Lower 30-Days Mortality in Adult COVID-19 Patients – A Register Study in Finland before COVID-19 Vaccines",not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Abstract 12870: Absence of LDL Measurement in Secondary Prevention is Associated With Increased Subsequent Major Adverse Clinical Event (MACE) That is Only Partially Mitigated by Statin Use,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
Efficacy and Safety of Atorvastatin and Ezetimibe (10/10mg) Fixed Dose Combination Versus Atorvastatin (20mg) Monotherapy in Bangladeshi Population,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
APOEGenotype and Statin Response: Evidence from Electronic Health Records in the UK Biobank and All of Us Research Program,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
Understanding the causes and consequences of low statin adherence: evidence from UK Biobank primary care data,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
HMG-CoA reductase inhibitors and the attenuation of risk for disseminated intravascular coagulation in patients with sepsis: Secondary analysis finds no change in the index outcome based on reason for statin prescription,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
Effects of Statin for Elderly Patients With Atherosclerotic Cardiovascular Disease,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
Evolocumab Plus Ezetimibe in High Risk Haemodialized Statin Intolerant Patients,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
Efficacy and Safety of Early Combined Therapy With PCSK9 Inhibitors and Statins in Acute Ischemic Stroke,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
A Multicenter Study to Evaluate the Effect of High Dose Rosuvastatin Versus Rosuvastatin and Ezetimibe in Stroke,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
Estimating prevalence and characteristics of statin intolerance among high and very high cardiovascular risk patients in Germany between 2017–2020,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
"Relationship Between Insulin Resistance and Statin Induced Type 2 Diabetes, and Integrative Personal Omics Profiling",not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
Effect of Simvastatin Withdrawal on Ocular Endothelial Function,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
Statin TReatment for COVID-19 to Optimise NeuroloGical recovERy,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
Envafolimab With Chemotherapy and Simvastatin in Advanced Biliary Tract Cancer,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
Randomized Comparison of Efficacy and Safety of High-intensity Rosuvastatin/Ezetimibe Combination Versus Treat-to-target Rosuvastatin Monotherapy for Patients With Peripheral Artery or Polyvascular Disease (CARE-PVD Trial),not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
STATIC - Statin Termination in Cancer,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
APOE Genotype and Statin Response: Evidence from the UK Biobank Baseline Assessment and Linked Mortality Data,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
Changes in Plaque Characteristics After Short-term Statin Therapy as Assessed With Coronary CT,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
Evaluate the Efficacy and Safety of Atorvastatin Combined With Temozolomide in the Treatment of Glioblastoma,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
Major Adverse Cardiovascular Events (MACE) in Rheumatoid Arthritis Patient With Moderate to Severe Disease Activity Treated With Tofacitinib and Statins vs TNF Inhibitors: TOFSTAT CLINICAL TRIAL,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
Effects of statin treatment on primary and hospital care use: a microsimulation model,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
Atorvastatin for Reduction of 28-day Mortality in COVID-19: RCT,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Statin Monotherapy or Statins in Combination With Ezetimibe in Patients for Prevention of CVD,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
The Effects of Rosuvastatin on Running Training Adaptation and Safety,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
Ursodeoxycholic Acid Attenuates Statin-Induced Impaired Glucose Tolerance,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
A randomised clinical trial of STAtin therapy for Reducing Events in the Elderly (STAREE): Statistical analysis plan,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Clinical validation of a statin-benefit polygenic score using real-world cohorts of primary prevention participants,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
Statin Reminders for Improving Prescribing in Primary Care,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
Statin Monotherapy for Treatment of Endocrine Metabolic Disease Risk,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
Effects of Atorvastatin in Graves' Orbitopathy (GO),not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
Intermediate-dose vs Standard Prophylactic Anticoagulation and Statin vs Placebo in ICU Patients With COVID-19,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
Pravastatin to Prevent Preeclampsia,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
StAtins for Venous Event Reduction in Patients With Venous Thromboembolism Pilot Study,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
A prospective study of hepatic safety of statins used in very elderly patients,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
TRIal of STatin Therapy Effect on Androgen Status and Erectile functioN in Men,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
Statins Against Bushfire Smoke,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
Statin Therapy With Atorvastatin in Surgical Aortic Valve Replacement,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
"A 12-Week, Phase 2 Study of Gemcabene in Hypercholesterolemia Patients on Stable Moderate and High-Intensity Statins",not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
MUscle Side-Effects of Atorvastatin in Coronary Patients,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
Effects of Simvastatin and Micronized Trans-resveratrol Treatment on Polycystic Ovary Syndrome (PCOS) Patients,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
Evaluation of Rosuvastatin Effect as Adjuvant Therapy to Methotrexate on Lipid Profile and the Possibility of its Cardioprotective Effect in Iraqi Patients with Active Rheumatoid Arthritis,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
Simvastatin Addition for Patients With Recent-onset Schizophrenia,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
Effect of Pravastatin in the Subjects With Prediabetes or Early Diabetes,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
Rosuvastatin for Prevention of Anthracycline-induced Cardiac Dysfunction in Breast Cancer Patients,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
Does Rosuvastatin Delay Progression of Atherosclerosis in HIV,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
Pravastatin Intervention to Delay Hepatocellular Carcinoma Recurrence,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
Atorvastatin Pretreatment in Cerebrovascular Events (APICES) After Flow Diverter Implantation,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
Carvedilol + Simvastatin vs. Carvedilol Alone for Cirrhosis and Cirrhotic Cardiomyopathy and Impact on Hepatic Decompensation and Survival,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
Comparison of Pitavastatin Plus Ezetimibe Versus High-Intensity Statin Therapy on Risk of New-Onset Diabetes Mellitus,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
Moderate-intensity Statin vs. Individualized LDL-C Target-based Therapy in Older Adults With Type 2 Diabetes (iTARGET-Elderly Study),not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
"**Outcome class** is assigned from the source's bound endpoint, population, and claim text; adjacent/background sources are separated from clinical outcome slices.",not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
"**Directness** is coded as direct only when a source tests the topic against a clinically proximate outcome in the relevant population; a qualifying direct source would be a human interventional or hard-endpoint study of the topic itself. Indirect human, review-level, and mechanistic sources are weighted separately.",not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
"**Directional signal** is counted within the assigned outcome class only. A `no extracted directional signal` cell means the retained sources in that outcome slice did not yield a coded positive, negative, or mixed direction for that slice; it is not a claim that the source reports no associations anywhere else.",not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
**Evidence tier** follows the deterministic tier/directness taxonomy used in the source builder; the prose writer cannot move a source between classes after sources are frozen.,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
Efficacy and Safety of Atorvastatin 2025,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
Effects of Statin for Elderly 2023,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
Evolocumab Plus Ezetimibe 2020,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
TRIal of STatin Therapy n.d.,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
Multicenter Study to Evaluate 2023,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
Efficacy and Safety of Early 2026,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
Estimating Prevalence and Characteristics 2022,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
Statins Against Bushfire n.d.,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
Relationship between Insulin Resistance 2020,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
Statin Therapy with Atorvastatin n.d.,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
Week Phase Study 2017,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
Effect of Simvastatin Withdrawal 2020,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
MUscle Side-Effects of Atorvastatin 2019,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
Statin TReatment for COVID 2025,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
PCOS 2017,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
Envafolimab with Chemotherapy and Simvastatin 2026,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
Evaluation of Rosuvastatin Effect 2017,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
Randomized Comparison of Efficacy 2026,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
STATIC Statin Termination 2026,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
Atorvastatin for Reduction of Day 2021,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
Changes in Plaque Characteristics 2026,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
Effect of Pravastatin in the Subjects 2017,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
Evaluate the Efficacy and Safety 2026,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
MACE 2026,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
Rosuvastatin for Prevention of Anthracycline-induced n.d.,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
Simvastatin Addition for Patients 2019,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
Statin Monotherapy or Statins 2021,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
APICES n.d.,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
Carvedilol Simvastatin vs Carvedilol n.d.,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
Comparison of Pitavastatin Plus n.d.,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
Does Rosuvastatin Delay 2018,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
Effects of Atorvastatin in Graves' 2021,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
Intermediate-dose vs Standard Prophylactic 2021,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
Moderate-intensity Statin vs Individualized n.d.,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
Pravastatin Intervention to Delay 2018,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
Pravastatin to Prevent Preeclampsia 2021,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
Statin Monotherapy for Treatment 2022,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
Statin Reminders for Improving 2024,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
StAtins for Venous Event 2020,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
Effects of Rosuvastatin on Running 2026,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
Ursodeoxycholic Acid Attenuates 2026,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation

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