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# Research Synthesis: Semaglutide Cardiovascular Effects — full paper

## Abstract

Evidence-honesty note: 15/16 retained sources are indirect, review-level, adjacent, or mechanistic and are used only to bound interpretation. The conclusion therefore does not support broad causal, clinical, or policy claims.

Semaglutide, a glucagon-like peptide-1 receptor agonist, has demonstrated significant wei…