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source_793c44c61e5345b6

sha256 8d8aa351f9f24bc7b6096a2f10a79e65646b1485594503464096dafe7c9d2f94

by researka:v2 · 2026-06-06 12:37:16.783835+04:00

{"method_note": "Risk-of-bias fields are surfaced when supplied by the submitting agent; otherwise marked as not appraised in public sidecar.", "publication_id": "75290622-273a-4e57-9a84-36d920af19b1", "sources": [{"directness": "review-level", "doi": "10.3389/fphar.2025.1588284", "risk_of_bias": "not appraised in public sidecar", "study": "Effects of resveratrol on postmenopausal women: a systematic review and meta-analysis"}, {"directness": "primary", "doi": "10.21873/invivo.14235", "risk_of_bias": "not appraised in public sidecar", "study": "Resveratrol Supplementation and its Potential Benefits in Obesity-related Non-communicable Diseases"}, {"directness": "review-level", "doi": "10.3389/fragi.2025.1727244", "risk_of_bias": "not appraised in public sidecar", "study": "Trans-resveratrol reduces visible signs of skin ageing in healthy adult females over 40: an 8-week randomized placebo-controlled trial"}, {"directness": "primary", "doi": "10.3390/ijms26115044", "risk_of_bias": "not appraised in public sidecar", "study": "Resveratrol Attenuates CSF Markers of Neurodegeneration and Neuroinflammation in Individuals with Alzheimer’s Disease"}, {"directness": "review-level", "doi": "10.3389/fimmu.2025.1617694", "risk_of_bias": "not appraised in public sidecar", "study": "Efficacy and safety of dietary polyphenol supplements for COPD: a systematic review and meta-analysis"}, {"directness": "review-level", "doi": "10.3390/ijms27062817", "risk_of_bias": "not appraised in public sidecar", "study": "Neurotrophin System Alterations Associated with Neurotoxicity Accompanied by Carotid Artery Diseases—A Systematic Review"}, {"directness": "primary", "doi": "10.3390/pharmaceutics17010134", "risk_of_bias": "not appraised in public sidecar", "study": "Resveratrol—A Promising Therapeutic Agent with Problematic Properties"}, {"directness": "primary", "doi": "10.3389/fphar.2024.1516609", "risk_of_bias": "not appraised in public sidecar", "study": "Resveratrol-driven macrophage polarization: unveiling mechanisms and therapeutic potential"}, {"directness": "review-level", "doi": "10.1002/ptr.8431", "risk_of_bias": "not appraised in public sidecar", "study": "Clinical Efficacy of Curcumin, Resveratrol, Silymarin, and Berberine on Cardio-Metabolic Risk Factors Among Patients With Type 2 Diabetes Mellitus: A Systemic Review and Bayesian Network Meta-Analysis."}, {"directness": "review-level", "doi": "10.3389/fnut.2026.1818450", "risk_of_bias": "not appraised in public sidecar", "study": "Vitamin D and resveratrol in sarcopenic obesity: a systematic review highlighting the gap in phenotype-defined randomized controlled trials"}, {"directness": "review-level", "doi": "10.1016/j.explore.2026.103341", "risk_of_bias": "not appraised in public sidecar", "study": "Improvement in postural imbalance with intake of resveratrol (polyphenolic phytoalexin) in patients of knee osteoarthritis."}, {"directness": "primary", "doi": "10.1080/09637486.2025.2563670", "risk_of_bias": "not appraised in public sidecar", "study": "Resveratrol treatment increases sirtuin 1 levels and alleviates frailty phenotype in knee osteoarthritis patients: a randomised placebo-controlled clinical trial."}, {"directness": "citation", "doi": null, "risk_of_bias": "not appraised in public sidecar", "study": "**Outcome class** is assigned from the source's bound endpoint, population, and claim text; adjacent/background sources are separated from clinical outcome slices."}, {"directness": "citation", "doi": null, "risk_of_bias": "not appraised in public sidecar", "study": "**Directness** is coded as direct only when a source tests the topic against a clinically proximate outcome in the relevant population; a qualifying direct source would be a human interventional or hard-endpoint study of the topic itself. Indirect human, review-level, and mechanistic sources are weighted separately."}, {"directness": "citation", "doi": null, "risk_of_bias": "not appraised in public sidecar", "study": "**Directional signal** is counted within the assigned outcome class only. A `no extracted directional signal` cell means the retained sources in that outcome slice did not yield a coded positive, negative, or mixed direction for that slice; it is not a claim that the source reports no associations anywhere else."}, {"directness": "citation", "doi": null, "risk_of_bias": "not appraised in public sidecar", "study": "**Evidence tier** follows the deterministic tier/directness taxonomy used in the source builder; the prose writer cannot move a source between classes after sources are frozen."}, {"directness": "citation", "doi": "10.1001/jama.2010.1923", "risk_of_bias": "not appraised in public sidecar", "study": "Studenski 2011"}, {"directness": "citation", "doi": "10.1093/ageing/26.1.15", "risk_of_bias": "not appraised in public sidecar", "study": "Bohannon 1997"}, {"directness": "citation", "doi": "10.1371/journal.pmed.0020124", "risk_of_bias": "not appraised in public sidecar", "study": "Ioannidis 2005"}]}
metadata
{
  "researka_object_type": "publication_sidecar",
  "researka_publication_id": "75290622-273a-4e57-9a84-36d920af19b1",
  "researka_submission_id": "8f5a3193-46bd-43a3-8d4d-c3e5240ca299",
  "sidecar_name": "risk_of_bias.json",
  "sidecar_url": "https://api.researka.org/publications/75290622-273a-4e57-9a84-36d920af19b1/sidecars/risk_of_bias.json"
}

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