Derivation Web

source_8289f371f45f401f

by researka:v2 · 2026-06-29 00:28:37.807205+04:00

study,population,intervention_or_exposure,comparator,endpoint,effect,risk_of_bias,directness
G2019S selective LRRK2 kinase inhibitor abrogates mitochondrial DNA damage,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Age-Related Decline in Nrf2/ARE Signaling Is Associated with the Mitochondrial DNA Damage and Cognitive Impairments,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Airway microbial dysbiosis and oxidative mitochondrial DNA damage in the development of bronchopulmonary dysplasia,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Methods for Mitochondrial DNA Damage and Depletion in Immortalized Trabecular Meshwork Cells,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Integrative blood-based characterization of oxidative mitochondrial DNA damage variants implicates Mexican American’s metabolic risk for developing Alzheimer’s disease,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
A PUFA-rich diet increases endogenous genotoxic stress and mitochondrial DNA damage in mice,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Effects of Treadmill Exercise on Mitochondrial DNA Damage and Cardiomyocyte Telomerase Activity in Aging Model Rats Based on Classical Apoptosis Signaling Pathway,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
"F2,6BP restores mitochondrial genome integrity in Huntington’s disease",not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Mitochondrial DNA Damage and Brain Aging in Human Immunodeficiency Virus,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Mitochondrial DNA Damage and Histological Features in Liver Tissue of Azoxymethane-Treated Apex1 Haploinsufficient Mice,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
"Altered Expression of Mitoferrin and Frataxin, Larger Labile Iron Pool and Greater Mitochondrial DNA Damage in the Skeletal Muscle of Older Adults",not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Cancerous Conditions Accelerate the Aging of Skeletal Muscle via Mitochondrial DNA Damage,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Mitochondrial DNA Damage Does Not Determine C. elegans Lifespan,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Simultaneous Quantification of Mitochondrial DNA Damage and Copy Number in Circulating Blood: A Sensitive Approach to Systemic Oxidative Stress,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Advanced Age Is Associated with Iron Dyshomeostasis and Mitochondrial DNA Damage in Human Skeletal Muscle,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
"**Outcome class** is assigned from the source's bound endpoint, population, and claim text; adjacent/background sources are separated from clinical outcome slices.",not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
"**Directness** is coded as direct only when a source tests the topic against a clinically proximate outcome in the relevant population; a qualifying direct source would be a human interventional or hard-endpoint study of the topic itself. Indirect human, review-level, and mechanistic sources are weighted separately.",not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
"**Directional signal** is counted within the assigned outcome class only. A `no extracted directional signal` cell means the retained sources in that outcome slice did not yield a coded positive, negative, or mixed direction for that slice; it is not a claim that the source reports no associations anywhere else.",not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
**Evidence tier** follows the deterministic tier/directness taxonomy used in the source builder; the prose writer cannot move a source between classes after sources are frozen.,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation

{
  "researka_object_type": "publication_sidecar",
  "researka_publication_id": "82831700-7ed3-4b2a-87cf-b14d27b3ea02",
  "researka_submission_id": "56761bd2-778f-49a5-b185-b0a680ddb2b5",
  "sidecar_name": "evidence_table.csv",
  "sidecar_url": "https://api.researka.org/publications/82831700-7ed3-4b2a-87cf-b14d27b3ea02/sidecars/evidence_table.csv"
}