Derivation Web

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# Alpha memo: activated mortality severe endpoint split

**One-sentence alpha:** Receipt 1 reports Survival differences were found between high and low levels of APTT for mortality using 50s as the optimal cut-off; Receipt 2 reports APC treatment did not alter the extent of circulating inflammatory cytokine levels at 3 or 24 hr after endotoxin exposure, so the claim is a bounded population/endpoin…