Derivation Web

source_87a2bd6e77aa49e5

# Source literature boundary memo

## Research question

Across retrieved source-level receipts for metformin, which endpoints show directionally favorable versus null/non-convergent signals, and what matched PICO remains untested?

## Selection criteria

The source-literature selector kept metformin because the candidate bundle met the public source rule: 5 citable papers, 5 distinct fact-backed …