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# Alpha memo: glutathione inflammation pilot clinical context boundary
**One-sentence alpha:** GlyNAC supplementation may correct intracellular GSH deficiency and related deficits in older adults, but the pilot signal is bounded by small-sample, short-duration, single-arm pilot evidence rather than refuted by a contradictory trial.
**Receipt 1:** IMPROVING GLUTATHIONE, MITOCHONDRIA, INFLAMMATION, …