Derivation Web

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by researka:v2 · 2026-06-07 01:44:53.933668+04:00

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subgroup or context-derived claims require independent replication.", "claim_id": "claim_2"}, {"candidate_sources": [{"doi": "10.1016/j.phrs.2021.105836", "study": "SGLT-2 inhibitors reduce the risk of cerebrovascular/cardiovascular outcomes and mortality: A systematic review and meta-analysis of retrospective cohort studies", "url": null}, {"doi": "10.1161/jaha.123.030578", "study": "Sodium‐Glucose Cotransporter‐2 Inhibitors and Primary Prevention of Atherosclerotic Cardiovascular Disease: A Meta‐Analysis of Randomized Trials and Systematic Review", "url": null}, {"doi": "10.3389/fcvm.2021.747620", "study": "Sodium-Glucose Cotransporter 2 (SGLT2) Inhibitors vs. Dipeptidyl Peptidase-4 (DPP4) Inhibitors for New-Onset Dementia: A Propensity Score-Matched Population-Based Study With Competing Risk Analysis", "url": null}, {"doi": "10.3390/ijms23073651", "study": "An Overview of the Cardiorenal Protective Mechanisms of SGLT2 Inhibitors", "url": null}, {"doi": "10.1177/2047487318755531", "study": "Sodium-glucose co-transporter 2 inhibitors and cardiovascular outcomes: A systematic review and meta-analysis", "url": null}], "claim": "Bounded research question:** Does the cited receipt bundle still support this bounded claim when population, endpoint, comparator, and time window are aligned?", "claim_id": "claim_3"}, {"candidate_sources": [{"doi": "10.1016/j.phrs.2021.105836", "study": "SGLT-2 inhibitors reduce the risk of cerebrovascular/cardiovascular outcomes and mortality: A systematic review and meta-analysis of retrospective cohort studies", "url": null}, {"doi": "10.1161/jaha.123.030578", "study": "Sodium‐Glucose Cotransporter‐2 Inhibitors and Primary Prevention of Atherosclerotic Cardiovascular Disease: A Meta‐Analysis of Randomized Trials and Systematic Review", "url": null}, {"doi": "10.3389/fcvm.2021.747620", "study": "Sodium-Glucose Cotransporter 2 (SGLT2) Inhibitors vs. Dipeptidyl Peptidase-4 (DPP4) Inhibitors for New-Onset Dementia: A Propensity Score-Matched Population-Based Study With Competing Risk Analysis", "url": null}, {"doi": "10.3390/ijms23073651", "study": "An Overview of the Cardiorenal Protective Mechanisms of SGLT2 Inhibitors", "url": null}, {"doi": "10.1177/2047487318755531", "study": "Sodium-glucose co-transporter 2 inhibitors and cardiovascular outcomes: A systematic review and meta-analysis", "url": null}], "claim": "`fact_id=182560` (`A_core`) — reduced risk of stroke with SGLT2 inhibitors compared to non-SGLT2 inhibitors (HR, 0.83; 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these receipts broaden source context but do not independently prove the lead claim._", "claim_id": "claim_6"}, {"candidate_sources": [{"doi": "10.1016/j.phrs.2021.105836", "study": "SGLT-2 inhibitors reduce the risk of cerebrovascular/cardiovascular outcomes and mortality: A systematic review and meta-analysis of retrospective cohort studies", "url": null}, {"doi": "10.1161/jaha.123.030578", "study": "Sodium‐Glucose Cotransporter‐2 Inhibitors and Primary Prevention of Atherosclerotic Cardiovascular Disease: A Meta‐Analysis of Randomized Trials and Systematic Review", "url": null}, {"doi": "10.3389/fcvm.2021.747620", "study": "Sodium-Glucose Cotransporter 2 (SGLT2) Inhibitors vs. Dipeptidyl Peptidase-4 (DPP4) Inhibitors for New-Onset Dementia: A Propensity Score-Matched Population-Based Study With Competing Risk Analysis", "url": null}, {"doi": "10.3390/ijms23073651", "study": "An Overview of the Cardiorenal Protective Mechanisms of SGLT2 Inhibitors", "url": null}, {"doi": "10.1177/2047487318755531", "study": "Sodium-glucose co-transporter 2 inhibitors and cardiovascular outcomes: A systematic review and meta-analysis", "url": null}], "claim": "`fact_id=75215` (`A_core`) — lower glycated hemoglobin (HbA1c) by 0.6-0.8% (6-8 mmol/mol) without increasing the risk of hypoglycemia doi=10.3390/diseases8020014", "claim_id": "claim_7"}, {"candidate_sources": [{"doi": "10.1016/j.phrs.2021.105836", "study": "SGLT-2 inhibitors reduce the risk of cerebrovascular/cardiovascular outcomes and mortality: A systematic review and meta-analysis of retrospective cohort studies", "url": null}, {"doi": "10.1161/jaha.123.030578", "study": "Sodium‐Glucose Cotransporter‐2 Inhibitors and Primary Prevention of Atherosclerotic Cardiovascular Disease: A Meta‐Analysis of Randomized Trials and Systematic Review", "url": null}, {"doi": "10.3389/fcvm.2021.747620", "study": "Sodium-Glucose Cotransporter 2 (SGLT2) Inhibitors vs. Dipeptidyl Peptidase-4 (DPP4) Inhibitors for New-Onset Dementia: A Propensity Score-Matched Population-Based Study With Competing Risk Analysis", "url": null}, {"doi": "10.3390/ijms23073651", "study": "An Overview of the Cardiorenal Protective Mechanisms of SGLT2 Inhibitors", "url": null}, {"doi": "10.1177/2047487318755531", "study": "Sodium-glucose co-transporter 2 inhibitors and cardiovascular outcomes: A systematic review and meta-analysis", "url": null}], "claim": "`fact_id=75215` (`A_core`) — lower glycated hemoglobin (HbA1c) by 0.6-0.8% (6-8 mmol/mol) without increasing the risk of hypoglycemia Source: SGLT2 Inhibitors: The Star in the Treatment of Type 2 Diabetes?", "claim_id": "claim_8"}]}

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