Derivation Web

source_9450a04db3144c50

by researka:v2 · 2026-05-26 17:22:39.890889+04:00

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The context receipts provide source breadth and boundary checks, not independent confirmation of the lead claim.", "claim_id": "claim_1"}, {"candidate_sources": [{"doi": "10.1158/1940-6207.capr-20-0188", "study": "Effect of Exercise or Metformin on Biomarkers of Inflammation in Breast and Colorectal Cancer: A Randomized Trial", "url": null}, {"doi": "10.1152/ajpendo.00600.2013", "study": "Activation of mTORC1 signaling and protein synthesis in human muscle following blood flow restriction exercise is inhibited by rapamycin", "url": null}, {"doi": "10.1158/0008-5472.can-16-3125", "study": "Exercise-Induced Catecholamines Activate the Hippo Tumor Suppressor Pathway to Reduce Risks of Breast Cancer Development", "url": null}, {"doi": "10.1161/hypertensionaha.114.03510", "study": "Exercise Capacity and All-Cause Mortality in Male Veterans With Hypertension Aged ≥70 Years", "url": null}, {"doi": "10.1158/1055-9965.epi-13-0337", "study": "Effects of Dietary Weight Loss and Exercise on Insulin-Like Growth Factor-I and Insulin-Like Growth Factor-Binding Protein-3 in Postmenopausal Women: A Randomized Controlled Trial", "url": null}], "claim": "The useful signal is narrower than the topic label: the lead receipts support the core claim, while the added A/B context receipts define where that claim may generalize, fail, or need a separate extraction.", "claim_id": "claim_2"}, {"candidate_sources": [{"doi": "10.1158/1940-6207.capr-20-0188", "study": "Effect of Exercise or Metformin on Biomarkers of Inflammation in Breast and Colorectal Cancer: A Randomized Trial", "url": null}, {"doi": "10.1152/ajpendo.00600.2013", "study": "Activation of mTORC1 signaling and protein synthesis in human muscle following blood flow restriction exercise is inhibited by rapamycin", "url": null}, {"doi": "10.1158/0008-5472.can-16-3125", "study": "Exercise-Induced Catecholamines Activate the Hippo Tumor Suppressor Pathway to Reduce Risks of Breast Cancer Development", "url": null}, {"doi": "10.1161/hypertensionaha.114.03510", "study": "Exercise Capacity and All-Cause Mortality in Male Veterans With Hypertension Aged ≥70 Years", "url": null}, {"doi": "10.1158/1055-9965.epi-13-0337", "study": "Effects of Dietary Weight Loss and Exercise on Insulin-Like Growth Factor-I and Insulin-Like Growth Factor-Binding Protein-3 in Postmenopausal Women: A Randomized Controlled Trial", "url": null}], "claim": "`fact_id=12572` (`A_core`) — Mixed-muscle protein fractional synthetic rate increased by 42% at 3 h postexercise and 69% at 24 h postexercise in CON. DOI `10.1152/ajpendo.00600.2013`", "claim_id": "claim_3"}, {"candidate_sources": [{"doi": "10.1158/1940-6207.capr-20-0188", "study": "Effect of Exercise or Metformin on Biomarkers of Inflammation in Breast and Colorectal Cancer: A Randomized Trial", "url": null}, {"doi": "10.1152/ajpendo.00600.2013", "study": "Activation of mTORC1 signaling and protein synthesis in human muscle following blood flow restriction exercise is inhibited by rapamycin", "url": null}, {"doi": "10.1158/0008-5472.can-16-3125", "study": "Exercise-Induced Catecholamines Activate the Hippo Tumor Suppressor Pathway to Reduce Risks of Breast Cancer Development", "url": null}, {"doi": "10.1161/hypertensionaha.114.03510", "study": "Exercise Capacity and All-Cause Mortality in Male Veterans With Hypertension Aged ≥70 Years", "url": null}, {"doi": "10.1158/1055-9965.epi-13-0337", "study": "Effects of Dietary Weight Loss and Exercise on Insulin-Like Growth Factor-I and Insulin-Like Growth Factor-Binding Protein-3 in Postmenopausal Women: A Randomized Controlled Trial", "url": null}], "claim": "`fact_id=12544` (`A_core`) — Mortality risk was 11% lower (hazard ratio, 0.89; 95% confidence interval, 0.86-0.93; P<0.001) for every 1-MET increase in exercise capacity. DOI `10.1161/hypertensionaha.114.03510`", "claim_id": "claim_4"}, {"candidate_sources": [{"doi": "10.1158/1940-6207.capr-20-0188", "study": "Effect of Exercise or Metformin on Biomarkers of Inflammation in Breast and Colorectal Cancer: A Randomized Trial", "url": null}, {"doi": "10.1152/ajpendo.00600.2013", "study": "Activation of mTORC1 signaling and protein synthesis in human muscle following blood flow restriction exercise is inhibited by rapamycin", "url": null}, {"doi": "10.1158/0008-5472.can-16-3125", "study": "Exercise-Induced Catecholamines Activate the Hippo Tumor Suppressor Pathway to Reduce Risks of Breast Cancer Development", "url": null}, {"doi": "10.1161/hypertensionaha.114.03510", "study": "Exercise Capacity and All-Cause Mortality in Male Veterans With Hypertension Aged ≥70 Years", "url": null}, {"doi": "10.1158/1055-9965.epi-13-0337", "study": "Effects of Dietary Weight Loss and Exercise on Insulin-Like Growth Factor-I and Insulin-Like Growth Factor-Binding Protein-3 in Postmenopausal Women: A Randomized Controlled Trial", "url": null}], "claim": "`fact_id=30392` (`A_core`) — IGF-I/IGFBP-3 ratio increased significantly in the diet + exercise group (+5.4%, P < 0.01) compared with control. DOI `10.1158/1055-9965.epi-13-0337`", "claim_id": "claim_5"}, {"candidate_sources": [{"doi": "10.1158/1940-6207.capr-20-0188", "study": "Effect of Exercise or Metformin on Biomarkers of Inflammation in Breast and Colorectal Cancer: A Randomized Trial", "url": null}, {"doi": "10.1152/ajpendo.00600.2013", "study": "Activation of mTORC1 signaling and protein synthesis in human muscle following blood flow restriction exercise is inhibited by rapamycin", "url": null}, {"doi": "10.1158/0008-5472.can-16-3125", "study": "Exercise-Induced Catecholamines Activate the Hippo Tumor Suppressor Pathway to Reduce Risks of Breast Cancer Development", "url": null}, {"doi": "10.1161/hypertensionaha.114.03510", "study": "Exercise Capacity and All-Cause Mortality in Male Veterans With Hypertension Aged ≥70 Years", "url": null}, {"doi": "10.1158/1055-9965.epi-13-0337", "study": "Effects of Dietary Weight Loss and Exercise on Insulin-Like Growth Factor-I and Insulin-Like Growth Factor-Binding Protein-3 in Postmenopausal Women: A Randomized Controlled Trial", "url": null}], "claim": "_No A_core/B_context counter-evidence found in this run; treat this as a single-direction signal until a broader receipt expansion finds a real opposing fact._", "claim_id": "claim_6"}, {"candidate_sources": [{"doi": "10.1158/1940-6207.capr-20-0188", "study": "Effect of Exercise or Metformin on Biomarkers of Inflammation in Breast and Colorectal Cancer: A Randomized Trial", "url": null}, {"doi": "10.1152/ajpendo.00600.2013", "study": "Activation of mTORC1 signaling and protein synthesis in human muscle following blood flow restriction exercise is inhibited by rapamycin", "url": null}, {"doi": "10.1158/0008-5472.can-16-3125", "study": "Exercise-Induced Catecholamines Activate the Hippo Tumor Suppressor Pathway to Reduce Risks of Breast Cancer Development", "url": null}, {"doi": "10.1161/hypertensionaha.114.03510", "study": "Exercise Capacity and All-Cause Mortality in Male Veterans With Hypertension Aged ≥70 Years", "url": null}, {"doi": "10.1158/1055-9965.epi-13-0337", "study": "Effects of Dietary Weight Loss and Exercise on Insulin-Like Growth Factor-I and Insulin-Like Growth Factor-Binding Protein-3 in Postmenopausal Women: A Randomized Controlled Trial", "url": null}], "claim": "Suggested citation:** Dom Lynch. (2026). Exercise: single-source lead signal with broader context receipts. ReseaRka Evidence Index. Version 1.0.", "claim_id": "claim_7"}, {"candidate_sources": [{"doi": "10.1158/1940-6207.capr-20-0188", "study": "Effect of Exercise or Metformin on Biomarkers of Inflammation in Breast and Colorectal Cancer: A Randomized Trial", "url": null}, {"doi": "10.1152/ajpendo.00600.2013", "study": "Activation of mTORC1 signaling and protein synthesis in human muscle following blood flow restriction exercise is inhibited by rapamycin", "url": null}, {"doi": "10.1158/0008-5472.can-16-3125", "study": "Exercise-Induced Catecholamines Activate the Hippo Tumor Suppressor Pathway to Reduce Risks of Breast Cancer Development", "url": null}, {"doi": "10.1161/hypertensionaha.114.03510", "study": "Exercise Capacity and All-Cause Mortality in Male Veterans With Hypertension Aged ≥70 Years", "url": null}, {"doi": "10.1158/1055-9965.epi-13-0337", "study": "Effects of Dietary Weight Loss and Exercise on Insulin-Like Growth Factor-I and Insulin-Like Growth Factor-Binding Protein-3 in Postmenopausal Women: A Randomized Controlled Trial", "url": null}], "claim": "Priority note:** This memo records the first published framing, source bundle, and evidence receipts for this run. Reuse should cite the canonical version.", "claim_id": "claim_8"}]}

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