Derivation Web

source_94633306253d4721

by researka:v2 · 2026-06-21 15:38:17.741604+04:00

study,population,intervention_or_exposure,comparator,endpoint,effect,risk_of_bias,directness
Ergothioneine promotes longevity and healthy aging in male mice,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
"Ergothioneine-rich water extracts of Hericium erinaceus HE-17 alleviate Alzheimer’s disease in mice by regulating oxidative stress, inflammation, and the gut microenvironment",not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Ergothioneine Ameliorates Alcoholic Fatty Liver Disease: A Dual Strategy of Accelerated Ethanol Elimination and Reducing Oxidative Stress,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Ergothioneine attenuates whole-abdominal irradiation-induced multi-organ injury via the gut-heart-brain axis by modulating calcium voltage-gated channel subunit alpha1 C (Cacna1c) expression,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
The Current Situation and Future Trends of Ergothioneine in Biology and Medical Research: A Bibliometric Analysis,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Engineering Escherichia coli for Ergothioneine Production via Metabolic Engineering and Fermentation Optimization,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Successful biosynthesis of natural antioxidant ergothioneine in Saccharomyces cerevisiae required only two genes from Grifola frondosa,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Ergothioneine rescues obesity-induced testicular dysfunction via dual restoration of steroidogenesis and mitochondrial redox homeostasis,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Enhanced production of ergothioneine in Aspergillus oryzae,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Ergothioneine as a potential protective agent against macular degeneration and other eye disorders,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Serum ergothioneine and risk of dementia in a general older Japanese population: the Hisayama Study,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Ergothioneine Attenuates Oxaliplatin-Induced Peripheral Neuropathy Without Compromising Antitumor Efficacy,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
The Association Between Serum Ergothioneine Concentration and Japanese Dietary Habits: The Third Survey of the ROAD Study,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
"Searching for a Longevity Food, We Bump into Hericium erinaceus Primordium Rich in Ergothioneine: The “Longevity Vitamin” Improves Locomotor Performances during Aging",not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Cognitive Healthy Aging in Mice: Boosting Memory by an Ergothioneine-Rich Hericium erinaceus Primordium Extract,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
"Uncovering the Potential Mechanisms of Ergothioneine in Neuroinflammation Through Network Pharmacology, Molecular Docking, Molecular Dynamics Simulation, and In Vitro Validation",not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Advances and prospects of ergothioneine in the treatment of cognitive frailty,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Ergothioneine Thione Spontaneously Binds to and Detaches from the Membrane Interphase,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Potential Protection Against Parkinson’s Disease by Ergothioneine—Nature’s Multifactorial Neuroprotectant,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
"Anserine, Balenine, and Ergothioneine: Impact of Histidine-Containing Compounds on Exercise Performance—A Narrative Review",not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
"Ergothioneine: An Antioxidative, Neuroprotective and Anti-Inflammatory Compound from Mushroom Residuals",not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
"**Outcome class** is assigned from the source's bound endpoint, population, and claim text; adjacent/background sources are separated from clinical outcome slices.",not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
"**Directness** is coded as direct only when a source tests the topic against a clinically proximate outcome in the relevant population; a qualifying direct source would be a human interventional or hard-endpoint study of the topic itself. Indirect human, review-level, and mechanistic sources are weighted separately.",not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
"**Directional signal** is counted within the assigned outcome class only. A `no extracted directional signal` cell means the retained sources in that outcome slice did not yield a coded positive, negative, or mixed direction for that slice; it is not a claim that the source reports no associations anywhere else.",not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
**Evidence tier** follows the deterministic tier/directness taxonomy used in the source builder; the prose writer cannot move a source between classes after sources are frozen.,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
Perera 2006,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
Cruz-Jentoft 2019,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
Ioannidis 2005,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation

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