Derivation Web

source_9538417351a44abf

by researka:v2 · 2026-06-06 20:28:34.919370+04:00

study,population,intervention_or_exposure,comparator,endpoint,effect,risk_of_bias,directness
Intermittent Supplementation With Fisetin Improves Physical Function and Decreases Cellular Senescence in Skeletal Muscle With Aging: A Comparison to Genetic Clearance of Senescent Cells and Synthetic Senolytic Approaches,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Biomarkers of cellular senescence predict risk of mild cognitive impairment: Results from the lifestyle interventions for elders (LIFE) study,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Associations between biomarkers of cellular senescence and physical function in humans: observations from the lifestyle interventions for elders (LIFE) study,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
A Systematic Review of the Role of Senescent Cells in Uterine Leiomyomas: Deciphering Molecular Pathways and Exploring Therapeutic Prospects,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
A proteomic atlas of senescence-associated secretomes for aging biomarker development,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Co-administration of vitamin D and N-acetylcysteine to modulate immunosenescence in older adults with vitamin D deficiency: a randomized clinical trial,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
Tranexamic acid protects human dermal fibroblasts from D-galactose-induced senescence via the GPR30/MAPK pathway,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
"Circulating Inflammatory, Mitochondrial Dysfunction, and Senescence-Related Markers in Older Adults with Physical Frailty and Sarcopenia: A BIOSPHERE Exploratory Study",not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Exploratory Effects of a Novel Nutraceutical on Senescence-Related Protein Biomarkers in Healthy Adults: A Pilot Proteomics Study,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Extracellular Nicotinamide Phosphoribosyltransferase Is a Component of the Senescence-Associated Secretory Phenotype,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
The cardio‐renal‐metabolic role of the nod‐like receptor protein‐3 and senescence‐associated secretory phenotype in early sodium/glucose cotransporter‐2 inhibitor therapy in people with diabetes who have had a myocardial infarction,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Cellular senescence in acute human infectious disease: a systematic review,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
Targeting cellular senescence in progenitor cells as a strategy to enhance bone regeneration by cell therapies: a systematic review of pre-clinical investigations,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,review-level
Microglial senescence contributes to female-biased neuroinflammation in the aging mouse hippocampus: implications for Alzheimer’s disease,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Cellular Senescence in Intervertebral Disc Aging and Degeneration: Molecular Mechanisms and Potential Therapeutic Opportunities,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
Global research trends in gut microbiota and cellular senescence: a bibliometric and visual analysis from 2015 to 2025,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
"Possible Mechanisms of Oxidative Stress-Induced Skin Cellular Senescence, Inflammation, and Cancer and the Therapeutic Potential of Plant Polyphenols",not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,primary
"**Outcome class** is assigned from the source's bound endpoint, population, and claim text; adjacent/background sources are separated from clinical outcome slices.",not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
"**Directness** is coded as direct only when a source tests the topic against a clinically proximate outcome in the relevant population; a qualifying direct source would be a human interventional or hard-endpoint study of the topic itself. Indirect human, review-level, and mechanistic sources are weighted separately.",not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
"**Directional signal** is counted within the assigned outcome class only. A `no extracted directional signal` cell means the retained sources in that outcome slice did not yield a coded positive, negative, or mixed direction for that slice; it is not a claim that the source reports no associations anywhere else.",not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
**Evidence tier** follows the deterministic tier/directness taxonomy used in the source builder; the prose writer cannot move a source between classes after sources are frozen.,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
Studenski 2011,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
Cesari 2009,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
Bohannon 1997,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation
Ioannidis 2005,not extracted,not extracted,not extracted,not extracted,not extracted,not appraised in public sidecar,citation

{
  "researka_object_type": "publication_sidecar",
  "researka_publication_id": "9725f21e-979b-4bf8-9bb0-9575b7741390",
  "researka_submission_id": "d84d61f4-83df-46e9-a204-7ad3a2b36c41",
  "sidecar_name": "evidence_table.csv",
  "sidecar_url": "https://api.researka.org/publications/9725f21e-979b-4bf8-9bb0-9575b7741390/sidecars/evidence_table.csv"
}