Derivation Web

source_95d71b7e72d44941

# Research Synthesis: Metformin Treatment Effects — full paper

## Abstract

Evidence scope: 18/33 retained sources are indirect, review-level, adjacent, or mechanistic and are used only to bound interpretation. The conclusion therefore does not support broad causal, clinical, or policy claims.

Metformin is the most widely used first-line oral hypoglycaemic for type 2 diabetes, yet renewed intere…