Derivation Web

source_9dc8370298614739

by researka:v2 · 2026-06-02 11:13:50.478830+04:00

{"publication_id": "456e9e42-fa00-477e-afb6-ba411ff85156", "traces": [{"candidate_sources": [{"doi": "10.1371/journal.pdig.0000015", "study": "Digital health interventions for gestational diabetes mellitus: A systematic review and meta-analysis of randomised controlled trials", "url": null}, {"doi": "10.3390/nu9050461", "study": "Effect of Probiotics on Metabolic Outcomes in Pregnant Women with Gestational Diabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials", "url": null}, {"doi": "10.3389/fmed.2021.699412", "study": "Mild Gestational Diabetes and Adverse Pregnancy Outcome: A Systemic Review and Meta-Analysis", "url": null}, {"doi": "10.1002/14651858.cd012327.pub2", "study": "Treatments for women with gestational diabetes mellitus: an overview of Cochrane systematic reviews", "url": null}, {"doi": "10.3390/ijms26052320", "study": "Unveiling Gestational Diabetes: An Overview of Pathophysiology and Management", "url": null}], "claim": "The cited A/B receipts support a specific working claim: HbA1c (-0.36%; -0.65 to -0.07); Probiotic supplementation was not effective in decreasing FBG (Mean Difference = -0.13; 95% CI -0.32, 0.06, p = 0.18). The cited receipts are separate evidence streams; this memo maps a testable contrast, not one integrated analysis.", "claim_id": "claim_1"}, {"candidate_sources": [{"doi": "10.1371/journal.pdig.0000015", "study": "Digital health interventions for gestational diabetes mellitus: A systematic review and meta-analysis of randomised controlled trials", "url": null}, {"doi": "10.3390/nu9050461", "study": "Effect of Probiotics on Metabolic Outcomes in Pregnant Women with Gestational Diabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials", "url": null}, {"doi": "10.3389/fmed.2021.699412", "study": "Mild Gestational Diabetes and Adverse Pregnancy Outcome: A Systemic Review and Meta-Analysis", "url": null}, {"doi": "10.1002/14651858.cd012327.pub2", "study": "Treatments for women with gestational diabetes mellitus: an overview of Cochrane systematic reviews", "url": null}, {"doi": "10.3390/ijms26052320", "study": "Unveiling Gestational Diabetes: An Overview of Pathophysiology and Management", "url": null}], "claim": "Interpretation note:** This is a hypothesis-generating alpha memo, not confirmatory evidence; subgroup or context-derived claims require independent replication.", "claim_id": "claim_2"}, {"candidate_sources": [{"doi": "10.1371/journal.pdig.0000015", "study": "Digital health interventions for gestational diabetes mellitus: A systematic review and meta-analysis of randomised controlled trials", "url": null}, {"doi": "10.3390/nu9050461", "study": "Effect of Probiotics on Metabolic Outcomes in Pregnant Women with Gestational Diabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials", "url": null}, {"doi": "10.3389/fmed.2021.699412", "study": "Mild Gestational Diabetes and Adverse Pregnancy Outcome: A Systemic Review and Meta-Analysis", "url": null}, {"doi": "10.1002/14651858.cd012327.pub2", "study": "Treatments for women with gestational diabetes mellitus: an overview of Cochrane systematic reviews", "url": null}, {"doi": "10.3390/ijms26052320", "study": "Unveiling Gestational Diabetes: An Overview of Pathophysiology and Management", "url": null}], "claim": "The most publishable angle here is not which intervention works, but why certain interventions achieve hard clinical endpoints (macrosomia, C-section) with only marginal glycemic improvement—and why others mechanistically succeed (probiotic HOMA-IR reduction) yet fail at every clinical glucose threshold. A second underexplored angle is the disproportionate respiratory distress syndrome risk (RR 3.2) in *mild* GDM, which exceeds the effect on macrosomia and points to glycemic-independent fetal pulmonary programming.", "claim_id": "claim_3"}, {"candidate_sources": [{"doi": "10.1371/journal.pdig.0000015", "study": "Digital health interventions for gestational diabetes mellitus: A systematic review and meta-analysis of randomised controlled trials", "url": null}, {"doi": "10.3390/nu9050461", "study": "Effect of Probiotics on Metabolic Outcomes in Pregnant Women with Gestational Diabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials", "url": null}, {"doi": "10.3389/fmed.2021.699412", "study": "Mild Gestational Diabetes and Adverse Pregnancy Outcome: A Systemic Review and Meta-Analysis", "url": null}, {"doi": "10.1002/14651858.cd012327.pub2", "study": "Treatments for women with gestational diabetes mellitus: an overview of Cochrane systematic reviews", "url": null}, {"doi": "10.3390/ijms26052320", "study": "Unveiling Gestational Diabetes: An Overview of Pathophysiology and Management", "url": null}], "claim": "Real tension: Probiotic supplementation significantly reduces HOMA-IR (-0.69, p=0.01) yet produces null effects on fasting blood glucose (-0.13, p=0.18) and LDL cholesterol (-0.16, p=0.67) in the same GDM population [3 vs 8 vs 2] — the insulin sensitivity gain does not translate to glycemic or lipid endpoints", "claim_id": "claim_4"}, {"candidate_sources": [{"doi": "10.1371/journal.pdig.0000015", "study": "Digital health interventions for gestational diabetes mellitus: A systematic review and meta-analysis of randomised controlled trials", "url": null}, {"doi": "10.3390/nu9050461", "study": "Effect of Probiotics on Metabolic Outcomes in Pregnant Women with Gestational Diabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials", "url": null}, {"doi": "10.3389/fmed.2021.699412", "study": "Mild Gestational Diabetes and Adverse Pregnancy Outcome: A Systemic Review and Meta-Analysis", "url": null}, {"doi": "10.1002/14651858.cd012327.pub2", "study": "Treatments for women with gestational diabetes mellitus: an overview of Cochrane systematic reviews", "url": null}, {"doi": "10.3390/ijms26052320", "study": "Unveiling Gestational Diabetes: An Overview of Pathophysiology and Management", "url": null}], "claim": "Bounded research question:** Does the cited receipt bundle still support this bounded claim when population, endpoint, comparator, and time window are aligned?", "claim_id": "claim_5"}, {"candidate_sources": [{"doi": "10.1371/journal.pdig.0000015", "study": "Digital health interventions for gestational diabetes mellitus: A systematic review and meta-analysis of randomised controlled trials", "url": null}, {"doi": "10.3390/nu9050461", "study": "Effect of Probiotics on Metabolic Outcomes in Pregnant Women with Gestational Diabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials", "url": null}, {"doi": "10.3389/fmed.2021.699412", "study": "Mild Gestational Diabetes and Adverse Pregnancy Outcome: A Systemic Review and Meta-Analysis", "url": null}, {"doi": "10.1002/14651858.cd012327.pub2", "study": "Treatments for women with gestational diabetes mellitus: an overview of Cochrane systematic reviews", "url": null}, {"doi": "10.3390/ijms26052320", "study": "Unveiling Gestational Diabetes: An Overview of Pathophysiology and Management", "url": null}], "claim": "`fact_id=73726` (`A_core`) — Lifestyle intervention versus usual care probably reduces large‐for‐gestational age (risk ratio (RR) 0.60, 95% confidence interval (CI) 0.50 to 0.71; 6 RCTs, N = 2994; GRADE moderate‐quality). doi=10.1002/14651858.cd012327.pub2", "claim_id": "claim_6"}]}

{
  "researka_object_type": "publication_sidecar",
  "researka_publication_id": "456e9e42-fa00-477e-afb6-ba411ff85156",
  "researka_submission_id": "d4d03688-b5f7-46d4-b9ad-45b2bdd009b7",
  "sidecar_name": "citation_traces.json",
  "sidecar_url": "https://api.researka.org/publications/456e9e42-fa00-477e-afb6-ba411ff85156/sidecars/citation_traces.json"
}