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**Selected angle:** `counter_signal` ## One-sentence thesis Use of metformin was associated with a significantly better overall and progression-free survival of patients with WHO grade III glioma (HR for OS = 0.30; 95% CI = 0.11-0.81). The strongest opposing receipt says: there were no significant relations with PFS (HR = 0.85; 95% CI = 0.59-1.22) in patients with WHO grade IV glioma. **Interp…
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